SELPLG Produkte
(Selectin P Ligand (SELPLG))
Kategorien
This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2011].
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Ausgewählte SELPLG Kategorien
SELPLG Antikörper
High quality antibodies with extensive validation data.
SELPLG ELISA Kits
Reliable ELISA kits for a wide range of species.
SELPLG Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene SELPLG Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
FACS, WB, ELISA, IHC (p)
Validierungen
- (4)
Kat. Nr.
ABIN679298
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
FACS
Validierungen
- (3)
Kat. Nr.
ABIN489932
Menge
100 tests
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (3)
Kat. Nr.
ABIN3022340
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene SELPLG ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6959335
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6959333
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (2)
- (1)
Kat. Nr.
ABIN6959334
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene SELPLG Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Cynomolgus
Source
HEK-293 Cells
Validierungen
- (2)
Kat. Nr.
ABIN7275485
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
HEK-293 Cells
Validierungen
- (2)
Kat. Nr.
ABIN7275487
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (2)
Kat. Nr.
ABIN6961157
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren SELPLG Produkten
: "Engineering Delivery of Nonbiologics Using Poly(lactic-co-glycolic acid) Nanoparticles for Repair of Disrupted Brain Endothelium." in: ACS omega, Vol. 5, Issue 24, pp. 14730-14740, (2020) (PubMed).: "Adhesion of Toxoplasma gondii tachyzoite-infected vehicle leukocytes to capillary endothelial cells triggers timely parasite egression." in: Scientific reports, Vol. 7, Issue 1, pp. 5675, (2019) (PubMed).
: "The intestinal nematode inhibits T-cell reactivity by targeting P-GP activity." in: Parasite immunology, Vol. 39, Issue 12, (2018) (PubMed).
: "C/EBPδ drives interactions between human MAIT cells and endothelial cells that are important for extravasation." in: eLife, Vol. 7, (2018) (PubMed).
: "Up-Regulated Expression of Matrix Metalloproteinases in Endothelial Cells Mediates Platelet Microvesicle-Induced Angiogenesis." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 41, Issue 6, pp. 2319-2332, (2017) (PubMed).
: "Histidine-Rich Glycoprotein Prevents Septic Lethality through Regulation of Immunothrombosis and Inflammation." in: EBioMedicine, Vol. 9, pp. 180-94, (2016) (PubMed).
: "Endoplasmic reticulum stress contributes to ferritin molecules-mediated macrophage migration via P-selectin glycoprotein ligand-1." in: Molecular nutrition & food research, Vol. 61, Issue 4, (2016) (PubMed).
: "Basic motifs target PSGL-1, CD43, and CD44 to plasma membrane sites where HIV-1 assembles." in: Journal of virology, Vol. 89, Issue 1, pp. 454-67, (2014) (PubMed).
: "Bromelain decreases neutrophil interactions with P-selectin, but not E-selectin, in vitro by proteolytic cleavage of P-selectin glycoprotein ligand-1." in: PLoS ONE, Vol. 8, Issue 11, pp. e78988, (2014) (PubMed).
: "Angiotensin II type 1A receptor signaling facilitates tumor metastasis formation through P-selectin-mediated interaction of tumor cells with platelets and endothelial cells." in: The American journal of pathology, Vol. 182, Issue 2, pp. 553-64, (2013) (PubMed).
Synonyme und alternative Namen zu SELPLG
selectin P ligand (SELPLG), selectin, platelet (p-selectin) ligand (Selplg), clasper (cla), selectin P ligand (Selplg), CD162, CLA, PSGL-1, Psgl-1, PSGL1, Psgl1, Selp1, SELPG, Selpl, SELPLGBezeichner auf Proteinebene für SELPLG
- P-selectin glycoprotein ligand 1
- cutaneous lymphocyte-associated associated antigen
- selectin P ligand
- P-selectin glycoprotein ligand 1 propeptide
- P-selectin glycoprotein ligand-1
- leukocyte cell surface adhesion molecule
- selectin, platelet (p-selectin) ligand
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