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SEMA4D/CD100 Produkte

(Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4D (SEMA4D))
Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Regulates dendrite and axon branching and morphogenesis. Promotes the migration of cerebellar granule cells and of endothelial cells. Plays a role in the immune system\; induces B-cells to aggregate and improves their viability (in vitro). Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Interaction with PLXNB1 mediates activation of RHOA (By similarity).

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Ausgewählte SEMA4D/CD100 Kategorien

SEMA4D/CD100 Antikörper

High quality antibodies with extensive validation data.

SEMA4D/CD100 ELISA Kits

Reliable ELISA kits for a wide range of species.

SEMA4D/CD100 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene SEMA4D/CD100 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation FACS, IHC, ELISA
Validierungen
  • (7)
Kat. Nr. ABIN5611304
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA
Validierungen
  • (1)
  • (3)
Kat. Nr. ABIN564579
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation FACS
Validierungen
  • (3)
Kat. Nr. ABIN7505849
Menge 100 tests
Datenblatt Datenblatt

Empfohlene SEMA4D/CD100 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (3)
  • (1)
Kat. Nr. ABIN6959355
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6962543
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6959356
Menge 96 tests
Datenblatt Datenblatt

Empfohlene SEMA4D/CD100 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (4)
Kat. Nr. ABIN7275566
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Cynomolgus
Source HEK-293 Cells
Validierungen
  • (3)
Kat. Nr. ABIN7275561
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (3)
Kat. Nr. ABIN7275565
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren SEMA4D/CD100 Produkten

Laber, Gadermaier, Wallwitz, Berg, Himmler: "A high-sensitivity enzyme immunoassay for the quantification of soluble human semaphorin 4D in plasma." in: Analytical biochemistry, Vol. 574, pp. 15-22, (2020) (PubMed).

Tsuda, Nishide, Maeda, Hayama, Koyama, Nojima, Takamatsu, Okuzaki, Morita, Nakatani, Kato, Nakanishi, Futami, Suga, Naito, Konaka, Satoh, Naito, Izumi, Obata, Nakatani, Shikina, Takeda, Hayama et al.: "Pathological and therapeutic implications of eosinophil-derived semaphorin 4D in eosinophilic chronic rhinosinusitis. ..." in: The Journal of allergy and clinical immunology, Vol. 145, Issue 3, pp. 843-854.e4, (2020) (PubMed).

Zou, Jiang, Dissanayaka, Heng, Xu, Gong, Huang, Zhang: "Sema4D/PlexinB1 promotes endothelial differentiation of dental pulp stem cells via activation of AKT and ERK1/2 signaling." in: Journal of cellular biochemistry, Vol. 120, Issue 8, pp. 13614-13624, (2019) (PubMed).

Terpos, Ntanasis-Stathopoulos, Christoulas, Bagratuni, Bakogeorgos, Gavriatopoulou, Eleutherakis-Papaiakovou, Kanellias, Kastritis, Dimopoulos: "Semaphorin 4D correlates with increased bone resorption, hypercalcemia, and disease stage in newly diagnosed patients with multiple myeloma." in: Blood cancer journal, Vol. 8, Issue 5, pp. 42, (2019) (PubMed).

Zou, Dissanayaka, Jiang, Wang, Heng, Huang, Zhang: "Semaphorin 4D Enhances Angiogenic Potential and Suppresses Osteo-/Odontogenic Differentiation of Human Dental Pulp Stem Cells." in: Journal of endodontics, Vol. 43, Issue 2, pp. 297-305, (2018) (PubMed).

Zhou, Li, Jin, Wu, He, Wang, Lei, Hu: "Sema4D/PlexinB1 inhibition ameliorates blood-brain barrier damage and improves outcome after stroke in rats." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 32, Issue 4, pp. 2181-2196, (2018) (PubMed).

Chen, Doumatey, Zhou, Lei, Bentley, Tekola-Ayele, Adebamowo, Baker, Fasanmade, Okafor, Eghan, Agyenim-Boateng, Amoah, Adebamowo, Acheampong, Johnson, Oli, Shriner, Adeyemo, Rotimi: "Genome-wide analysis identifies an african-specific variant in SEMA4D associated with body mass index." in: Obesity (Silver Spring, Md.), Vol. 25, Issue 4, pp. 794-800, (2017) (PubMed).

Li, He, Zhang, Guo, Zhou, Zhang, Wang, Zhao, Li, Zuo, Fan, Jia: "Interferon-α-induced CD100 on naïve CD8+ T cells enhances antiviral responses to hepatitis C infection through CD72 signal transduction." in: The Journal of international medical research, Vol. 45, Issue 1, pp. 89-100, (2017) (PubMed).

Anastasilakis, Polyzos, Makras, Gkiomisi, Sakellariou, Savvidis, Papatheodorou, Kokkoris, Terpos: "Circulating semaphorin-4D and plexin-B1 levels in postmenopausal women with low bone mass: the 3-month effect of zoledronic acid, denosumab or teriparatide treatment." in: Expert opinion on therapeutic targets, pp. 1-8, (2014) (PubMed).

He, Guo, Zhou, Zhang, Fan, Ji, Wang, Ma, Lian, Hao, Yao, Jia: "CD100 up-regulation induced by interferon-α on B cells is related to hepatitis C virus infection." in: PLoS ONE, Vol. 9, Issue 12, pp. e113338, (2014) (PubMed).

Synonyme und alternative Namen zu SEMA4D/CD100

semaphorin 4D (Sema4d), semaphorin 4D (SEMA4D), sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D (Sema4d), C9orf164, CD100, coll-4, COLL-4, M-sema-G, Semacl2, SEMAJ, Semaj, Semcl2

Bezeichner auf Proteinebene für SEMA4D/CD100

  • semaphorin-4D
  • A8
  • BB18
  • GR3
  • sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, 4D
  • M-sema G
  • sema J
  • semaphorin H
  • semaphorin-C-like 2
  • semaphorin-J
  • semaphorin 4D
  • collapsin-4
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