Septin 2 Produkte
(Septin 2 (SEPT2))
Kategorien
Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongation. Plays a role in ciliogenesis and collective cell movements. In cilia, required for the integrity of the diffusion barrier at the base of the primary cilium that prevents diffusion of transmembrane proteins between the cilia and plasma membranes (By similarity).
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Ausgewählte Septin 2 Kategorien
Septin 2 Antikörper
High quality antibodies with extensive validation data.
Septin 2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene Septin 2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC
Validierungen
- (4)
Kat. Nr.
ABIN308439
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF
Validierungen
- (3)
Kat. Nr.
ABIN518271
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC
Validierungen
- (2)
Kat. Nr.
ABIN7168865
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene Septin 2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6975081
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene Septin 2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7125024
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1319542
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1319544
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Septin 2 Produkten
: "Septin-2 is overexpressed in epithelial ovarian cancer and mediates proliferation via regulation of cellular metabolic proteins." in: Oncotarget, Vol. 10, Issue 31, pp. 2959-2972, (2019) (PubMed).: "Septins promote macropinosome maturation and traffic to the lysosome by facilitating membrane fusion." in: The Journal of cell biology, Vol. 214, Issue 5, pp. 517-27, (2016) (PubMed).
: "Septins arrange F-actin-containing fibers on the Chlamydia trachomatis inclusion and are required for normal release of the inclusion by extrusion." in: mBio, Vol. 5, Issue 5, pp. e01802-14, (2014) (PubMed).
: "Modulation of septin and molecular motor recruitment in the microtubule environment of the Taxol-resistant human breast cancer cell line MDA-MB-231." in: Proteomics, Vol. 11, Issue 19, pp. 3877-86, (2011) (PubMed).
: "Septins regulate actin organization and cell-cycle arrest through nuclear accumulation of NCK mediated by SOCS7." in: Cell, Vol. 130, Issue 5, pp. 837-50, (2007) (PubMed).
Synonyme und alternative Namen zu Septin 2
septin 2 (SEPT2), septin 2 (Sept2), septin 2 (sept2), septin 2 L homeolog (sept2.L), septin 2-like (SEPT2L), COG1487; VapC; putative nucleic acid-binding protein; contains PIN domain (sepT2), septin 2 S homeolog (sept2.S), AW208991, DIFF6, diff6, hNedd5, hnedd5, mKIAA0158, Nedd-5, NEDD5, Nedd5, nedd5, Pnutl3, pnutl3, Sep-02, sept2, SEPT2, sept2-B, septa, Septin-2, Septin-2A, Septin-2B, Septin-A, Vesp11, wu:fb52g01, wu:fb99a01, xlseptaBezeichner auf Proteinebene für Septin 2
- NEDD-5
- neural precursor cell expressed developmentally down-regulated protein 5
- neural precursor cell expressed, developmentally down-regulated 5
- septin-2
- neural precursor cell expressed, developmentally down-regulated gene 5
- vascular endothelial cell specific protein 11
- septin A
- septin-2A
- septin 2
- ANL34
- septin-2B
- Septin-2
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