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SET Domain, Bifurcated 1 Produkte

(SET Domain, Bifurcated 1 (SETDB1))

Kategorien

This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.[provided by RefSeq, Jun 2011].

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Ausgewählte SET Domain, Bifurcated 1 Kategorien

SET Domain, Bifurcated 1 Antikörper

High quality antibodies with extensive validation data.

SET Domain, Bifurcated 1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene SET Domain, Bifurcated 1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF
Validierungen
  • (4)
Kat. Nr. ABIN523280
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC
Validierungen
  • (3)
Kat. Nr. ABIN7155521
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Monkey, Mouse
Applikation WB, ELISA, ICC
Validierungen
  • (1)
  • (2)
Kat. Nr. ABIN969394
Menge 100 μL
Datenblatt Datenblatt

Empfohlene SET Domain, Bifurcated 1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6204130
Menge 96 tests
Datenblatt Datenblatt

Empfohlene SET Domain, Bifurcated 1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1319683
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1319685
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Baculovirus
Validierungen
  • (2)
Kat. Nr. ABIN2669700
Menge 20 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren SET Domain, Bifurcated 1 Produkten

Roy, Ghosh, Kumar, Chandran: "IFI16, a nuclear innate immune DNA sensor, mediates epigenetic silencing of herpesvirus genomes by its association with H3K9 methyltransferases SUV39H1 and GLP." in: eLife, Vol. 8, (2019) (PubMed).

Marco, Kisliouk, Tabachnik, Weller, Meiri et al.: "DNA CpG Methylation (5-Methylcytosine) and Its Derivative (5-Hydroxymethylcytosine) Alter Histone Posttranslational Modifications at the Pomc Promoter, Affecting the Impact of Perinatal Diet on ..." in: Diabetes, Vol. 65, Issue 8, pp. 2258-67, (2016) (PubMed).

Rodriguez-Paredes, Martinez de Paz, Simó-Riudalbas, Sayols, Moutinho, Moran, Villanueva, Vázquez-Cedeira, Lazo, Carneiro, Moura, Vieira, Teixeira, Esteller: "Gene amplification of the histone methyltransferase SETDB1 contributes to human lung tumorigenesis." in: Oncogene, Vol. 33, Issue 21, pp. 2807-13, (2014) (PubMed).

Skuland, Ovrevik, Låg, Schwarze, Refsnes: "Silica nanoparticles induce cytokine responses in lung epithelial cells through activation of a p38/TACE/TGF-α/EGFR-pathway and NF-κΒ signalling." in: Toxicology and applied pharmacology, Vol. 279, Issue 1, pp. 76-86, (2014) (PubMed).

Ceol, Houvras, Jane-Valbuena, Bilodeau, Orlando, Battisti, Fritsch, Lin, Hollmann, Ferré, Bourque, Burke, Turner, Uong, Johnson, Beroukhim, Mermel, Loda, Ait-Si-Ali, Garraway, Young, Zon: "The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset." in: Nature, Vol. 471, Issue 7339, pp. 513-7, (2011) (PubMed).

Gao, Yu, Bi, Jiang, Cui, Sun, Ma: "Akt/PKB interacts with the histone H3 methyltransferase SETDB1 and coordinates to silence gene expression." in: Molecular and cellular biochemistry, Vol. 305, Issue 1-2, pp. 35-44, (2007) (PubMed).

Gevaert, Staes, Van Damme, De Groot, Hugelier, Demol, Martens, Goethals, Vandekerckhove: "Global phosphoproteome analysis on human HepG2 hepatocytes using reversed-phase diagonal LC." in: Proteomics, Vol. 5, Issue 14, pp. 3589-99, (2005) (PubMed).

Ichimura, Watanabe, Sakamoto, Aoto, Fujita, Nakao: "Transcriptional repression and heterochromatin formation by MBD1 and MCAF/AM family proteins." in: The Journal of biological chemistry, Vol. 280, Issue 14, pp. 13928-35, (2005) (PubMed).

Sarraf, Stancheva: "Methyl-CpG binding protein MBD1 couples histone H3 methylation at lysine 9 by SETDB1 to DNA replication and chromatin assembly." in: Molecular cell, Vol. 15, Issue 4, pp. 595-605, (2004) (PubMed).

Wang, An, Cao, Xia, Erdjument-Bromage, Chatton, Tempst, Roeder, Zhang: "mAM facilitates conversion by ESET of dimethyl to trimethyl lysine 9 of histone H3 to cause transcriptional repression." in: Molecular cell, Vol. 12, Issue 2, pp. 475-87, (2003) (PubMed).

Synonyme und alternative Namen zu SET Domain, Bifurcated 1

SET domain bifurcated 1 (SETDB1), SET domain, bifurcated 1 (Setdb1), myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11 (MLLT11), histone-lysine N-methyltransferase SETDB1 (LOC100120014), histone-lysine N-methyltransferase SETDB1 (LOC100461671), SET domain, bifurcated 1a (setdb1a), SET domain bifurcated 1 L homeolog (setdb1.L), SET domain bifurcated 1 (Setdb1), SET domain, bifurcated 1b (setdb1b), AU022152, ESET, fc07d03, H3-K9-HMTase4, im:7143091, KG1T, KMT1E, mKIAA0067, NV10069, SETDB1, si:ch211-81a5.6, TDRD21, wu:fa04a12, wu:fc07d03, wu:fj80h02, zgc:152899

Bezeichner auf Proteinebene für SET Domain, Bifurcated 1

  • ERG-associated protein with SET domain
  • ERG-associated protein with a SET domain, ESET
  • H3-K9-HMTase 4
  • histone H3-K9 methyltransferase 4
  • histone-lysine N-methyltransferase SETDB1
  • histone-lysine N-methyltransferase, H3lysine-9 specific 4
  • lysine N-methyltransferase 1E
  • tudor domain containing 21
  • SET domain ERG-associated histone methyltransferase
  • SET domain, bifurcated 1
  • histone-lysine N-methyltransferase SETDB1-like
  • histone-lysine N-methyltransferase SETDB1-A
  • histone-lysine N-methyltransferase SETDB1-B
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