Ziege anti-Maus IgM Antikörper (AbBy Fluor® 488)

Produktnummer ABIN2176884

Produktdetails

Target: IgM

Reaktivität: Maus

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: AbBy Fluor® 488

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Aufreinigung: Purified by Protein A.

Isotyp: IgM

Anwendungsinformationen

Applikationshinweise: IF(IHC-P): (1:500-2000), IF(IHC-F): (1:500-2000), IF(ICC): (1:500-1000)
Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at 4 °C for 12 months.

Referenzen

Yu, Luo, Huang, Chen, Li, Qi, Gao: "Amino acids stimulate glycyl-tRNA synthetase nuclear localization for mammalian target of rapamycin expression in bovine mammary epithelial cells." in: Journal of cellular physiology, Vol. 234, Issue 5, pp. 7608-7621, (2019) (PubMed).

Zhang, Chen, Zhen, Ao, Yuan, Gao: "Annexin A2 positively regulates milk synthesis and proliferation of bovine mammary epithelial cells through the mTOR signaling pathway." in: Journal of cellular physiology, Vol. 233, Issue 3, pp. 2464-2475, (2017) (PubMed).

Antigendetails

Target: IgM

Abstract: IgM Produkte

Substanzklasse: Antibody

Hintergrund: Immunoglobulin IgM normally constitutes about 10 % of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and is largely confined to plasma due to it's large size. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells.