Ziege anti-Human IgG (Heavy & Light Chain) Antikörper (Agarose Beads)

Produktnummer ABIN233741

Hersteller Produkt- Nr.: 209-1150

Produktdetails

Target: IgG

Bindungsspezifität: Heavy & Light Chain

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Agarose Beads

Applikation: Immunoprecipitation (IP)

Hersteller Produkt- Nr.: 209-1150

Hersteller: Rockland

Verwendungszweck: Human IgG Antibody Agarose

Kreuzreaktivität (Details): Sufficient antibody capacity is provided to bind a minimum of 5 mg of pure Human IgG.

Produktmerkmale: CRP (C-Reactive Protein) belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. It promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. CRP can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. Diseases associated with CRP include Acute Pancreatitis and Appendicitis. Anti-CRP Antibody is ideal for researchers interested in cAMP Dependent PKA, IL6 signaling, calcium ion binding, and cholesterol binding.

Aufreinigung: This product is an IgG fraction antibody coupled to activated agarose.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Application Note: Anti-Human IgG Agarose Conjugate is useful for immunoprecipitation and other immunological assays. Immunoprecipitation Dilution: User Optimized

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 10 mg/mL

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: None

, Preservative:0.01 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store vial at 4° C prior to opening. DO NOT FREEZE.

Haltbarkeit: 12 months

Antigendetails

Target: IgG

Abstract: IgG Produkte

Substanzklasse: Antibody

Hintergrund: It is a protein complex composed of four peptide chains - two identical heavy chains and two identical light chains arranged in a Y-shape typical of antibody monomers. Each IgG has two antigen binding sites. Representing approximately 75 % of serum immunoglobulins in humans, IgG is the most abundant antibody isotype found in the circulation. IgG molecules are synthesized and secreted by plasma B cells. Secondary Antibodies are available in a variety of formats and conjugate types. When choosing a secondary antibody product, consideration must be given to species and immunoglobulin specificity, conjugate type, fragment and chain specificity, level of cross-reactivity, and host-species source and fragment composition.