The antibody SC-05 reacts with 80 kDa human secretory component glycoprotein (both free and bound in secretory IgA). Recognized glycoprotein is specific membrane marker of glandular carcinomas.
Kreuzreaktivität (Details)
Human
Aufreinigung
Purified by protein-A affinity chromatography.
Reinheit
> 95 % (by SDS-PAGE)
Endotoxin-Niveau
Low Endotoxin
Immunogen
Affinity-purified secretory component from human colostrum.
Klon
SC-05
Isotyp
IgG1
Applikationshinweise
Immunohistochemistry (frozen sections): Examples of positive human tissues: secretory mucosa of gastrointestinal and respiratory tract, epithelia of salivary glands, endometrium, endocervix, kidney, prostate, mammary gland. Recommended dilution: 2-8 μg/mL.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
1 mg/mL
Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Do not freeze.
Lagerung
4 °C
Informationen zur Lagerung
Store at 2-8°C. Do not freeze.
Bartek, Bartkova, Taylor-Papadimitriou: "Keratin 19 expression in the adult and developing human mammary gland." in: The Histochemical journal, Vol. 22, Issue 10, pp. 537-44, (1991) (PubMed).
Kvale, Bartek, Sollid, Brandtzaeg: "Rapid selection of cultured cells with increased expression of a membrane marker (secretory component)." in: International journal of cancer. Journal international du cancer, Vol. 42, Issue 4, pp. 638-41, (1988) (PubMed).