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SF3B2 Produkte

(Splicing Factor 3b, Subunit 2, 145kDa (SF3B2))

Kategorien

This gene encodes subunit 2 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 2 associates with pre-mRNA upstream of the branch site at the anchoring site. Subunit 2 also interacts directly with subunit 4 of the splicing factor 3b complex. Subunit 2 is a highly hydrophilic protein with a proline-rich N-terminus and a glutamate-rich stretch in the C-terminus. [provided by RefSeq, Jul 2008].

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Ausgewählte SF3B2 Kategorien

SF3B2 Antikörper

High quality antibodies with extensive validation data.

SF3B2 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene SF3B2 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF, IHC (p)
Validierungen
  • (6)
Kat. Nr. ABIN564766
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IF
Validierungen
  • (12)
Kat. Nr. ABIN6147666
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation IHC, IF
Validierungen
  • (4)
Kat. Nr. ABIN7261828
Menge 200 μL
Datenblatt Datenblatt

Empfohlene SF3B2 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6207545
Menge 96 tests
Datenblatt Datenblatt

Empfohlene SF3B2 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1319711
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1319713
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3095477
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren SF3B2 Produkten

Murthy, Bluemn, Gupta, Reimer, Rao, Pillai, Minella: "Cyclin-dependent kinase 1 (CDK1) and CDK2 have opposing roles in regulating interactions of splicing factor 3B1 with chromatin." in: The Journal of biological chemistry, Vol. 293, Issue 26, pp. 10220-10234, (2018) (PubMed).

Zheng, Xue, Shen, Li, Ma, Gong, Liu, Qiao, Xie, Lian, Sun, Zhao, Yao, Zuo, Li, Wang, Hu, Shao: "PHF5A Epigenetically Inhibits Apoptosis to Promote Breast Cancer Progression." in: Cancer research, Vol. 78, Issue 12, pp. 3190-3206, (2018) (PubMed).

Yang, Hadjikyriacou, Xia, Gayatri, Kim, Zurita-Lopez, Kelly, Guo, Li, Clarke, Bedford: "PRMT9 is a type II methyltransferase that methylates the splicing factor SAP145." in: Nature communications, Vol. 6, pp. 6428, (2015) (PubMed).

Tresini, Warmerdam, Kolovos, Snijder, Vrouwe, Demmers, van IJcken, Grosveld, Medema, Hoeijmakers, Mullenders, Vermeulen, Marteijn: "The core spliceosome as target and effector of non-canonical ATM signalling." in: Nature, Vol. 523, Issue 7558, pp. 53-8, (2015) (PubMed).

Synonyme und alternative Namen zu SF3B2

splicing factor 3b, subunit 2 (Sf3b2), splicing factor 3b subunit 2 (SF3B2), splicing factor 3B subunit 2 (LOC714747), splicing factor 3b subunit 2 L homeolog (sf3b2.L), splicing factor 3b subunit 2 (sf3b2), 145kDa, 2610311M13Rik, 2810441F20Rik, B230398H18Rik, cus1, Cus1, SAP145, sap145, SF3b1, SF3B2, SF3b145, sf3b145, SF3B145, SF3b150, sf3b150

Bezeichner auf Proteinebene für SF3B2

  • splicing factor 3B subunit 2
  • splicing factor 3b, subunit 2, 145kDa
  • splicing factor 3B subunit 2-like
  • SAP 145
  • pre-mRNA splicing factor SF3b 145 kDa subunit
  • pre-mRNA-splicing factor SF3b 145 kDa subunit
  • spliceosome associated protein 145
  • spliceosome-associated protein 145
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