SH2B3 Produkte
(SH2B Adaptor Protein 3 (SH2B3))
Kategorien
This gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin-dependent diabetes mellitus.[provided by RefSeq, May 2010].
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Ausgewählte SH2B3 Kategorien
SH2B3 Antikörper
High quality antibodies with extensive validation data.
SH2B3 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene SH2B3 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, FACS
Validierungen
- (2)
Kat. Nr.
ABIN6243723
Menge
50 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (2)
Kat. Nr.
ABIN185272
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, IF, ICC
Validierungen
- (1)
Kat. Nr.
ABIN6265048
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene SH2B3 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7405777
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7417174
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3077021
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren SH2B3 Produkten
: "CXM: a new tool for mapping breast cancer risk in the tumor microenvironment." in: Cancer research, Vol. 74, Issue 22, pp. 6419-29, (2014) (PubMed).: "Lnk inhibits myeloproliferative disorder-associated JAK2 mutant, JAK2V617F." in: Journal of leukocyte biology, Vol. 85, Issue 6, pp. 957-65, (2009) (PubMed).
: "Adaptor protein Lnk negatively regulates the mutant MPL, MPLW515L associated with myeloproliferative disorders." in: Blood, Vol. 110, Issue 9, pp. 3360-4, (2007) (PubMed).
: "The adaptor molecule Lnk negatively regulates tumor necrosis factor-alpha-dependent VCAM-1 expression in endothelial cells through inhibition of the ERK1 and -2 pathways." in: The Journal of biological chemistry, Vol. 281, Issue 29, pp. 20148-59, (2006) (PubMed).
: "Lnk inhibits Tpo-mpl signaling and Tpo-mediated megakaryocytopoiesis." in: The Journal of experimental medicine, Vol. 200, Issue 5, pp. 569-80, (2004) (PubMed).
: "Cloning and characterization of human Lnk, an adaptor protein with pleckstrin homology and Src homology 2 domains that can inhibit T cell activation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 164, Issue 10, pp. 5199-206, (2000) (PubMed).
Synonyme und alternative Namen zu SH2B3
SH2B adaptor protein 3 (SH2B3), SH2B adaptor protein 3 (Sh2b3), AI429800, IDDM20, LNK, LnkBezeichner auf Proteinebene für SH2B3
- lymphocyte adaptor protein
- SH2B adapter protein 3
- lymphocyte-specific adapter protein Lnk
- signal transduction protein Lnk
- linker of T-cell receptor pathways
- lymphocyte adapter protein
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