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Shugoshin Produkte

(Shugoshin 1 (SGOL1))

Kategorien

Plays a central role in chromosome cohesion during mitosis by preventing premature dissociation of cohesin complex from centromeres after prophase, when most of cohesin complex dissociates from chromosomes arms. May act by preventing phosphorylation of the stag2 subunit of cohesin complex at the centromere, ensuring cohesin persistence at centromere until cohesin cleavage by espl1/separase at anaphase. May regulate kinetochore microtubule stability in mitosis, possibly to sense tension on mitotic chromosomes.

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Ausgewählte Shugoshin Kategorien

Shugoshin Antikörper

High quality antibodies with extensive validation data.

Shugoshin Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene Shugoshin Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation ELISA, WB, IP
Validierungen
  • (9)
  • (4)
Kat. Nr. ABIN566873
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, WB, IF
Validierungen
  • (3)
Kat. Nr. ABIN7169545
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Schizosaccharomyces pombe
Applikation WB, IF
Validierungen
  • (3)
  • (3)
Kat. Nr. ABIN2452123
Menge 100 μL
Datenblatt Datenblatt

Empfohlene Shugoshin ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Qualitative Cell ELISA
Validierungen
Kat. Nr. ABIN5648311
Menge 96 tests
Datenblatt Datenblatt

Empfohlene Shugoshin Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1801995
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3095407
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3137055
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren Shugoshin Produkten

Nijenhuis, Vallardi, Teixeira, Kops, Saurin: "Negative feedback at kinetochores underlies a responsive spindle checkpoint signal." in: Nature cell biology, Vol. 16, Issue 12, pp. 1257-64, (2014) (PubMed).

Nobumori, Shouse, Wu, Lee, Shen, Liu: "B56? tumor-associated mutations provide new mechanisms for B56?-PP2A tumor suppressor activity." in: Molecular cancer research : MCR, Vol. 11, Issue 9, pp. 995-1003, (2013) (PubMed).

Wang, Mayer, Stemmann, Nigg: "Centromere DNA decatenation depends on cohesin removal and is required for mammalian cell division." in: Journal of cell science, Vol. 123, Issue Pt 5, pp. 806-13, (2010) (PubMed).

Shouse, Nobumori, Liu: "A B56gamma mutation in lung cancer disrupts the p53-dependent tumor-suppressor function of protein phosphatase 2A." in: Oncogene, Vol. 29, Issue 27, pp. 3933-41, (2010) (PubMed).

Nozawa, Nagao, Masuda, Iwasaki, Hirota, Nozaki, Kimura, Obuse: "Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation." in: Nature cell biology, Vol. 12, Issue 7, pp. 719-27, (2010) (PubMed).

Garcia-Cruz, Brieño, Roig, Grossmann, Velilla, Pujol, Cabero, Pessarrodona, Barbero, Garcia Caldés: "Dynamics of cohesin proteins REC8, STAG3, SMC1 beta and SMC3 are consistent with a role in sister chromatid cohesion during meiosis in human oocytes." in: Human reproduction (Oxford, England), Vol. 25, Issue 9, pp. 2316-27, (2010) (PubMed).

Hayashi-Takanaka, Yamagata, Nozaki, Kimura: "Visualizing histone modifications in living cells: spatiotemporal dynamics of H3 phosphorylation during interphase." in: The Journal of cell biology, Vol. 187, Issue 6, pp. 781-90, (2009) (PubMed).

Yamagishi, Sakuno, Shimura, Watanabe: "Heterochromatin links to centromeric protection by recruiting shugoshin." in: Nature, Vol. 455, Issue 7210, pp. 251-5, (2008) (PubMed).

Fu, Ding, Yuan, Aikhionbare, Yao, Cai, Jiang, Yao: "Phosphorylation of human Sgo1 by NEK2A is essential for chromosome congression in mitosis." in: Cell research, Vol. 17, Issue 7, pp. 608-18, (2007) (PubMed).

Thein, Kleylein-Sohn, Nigg, Gruneberg: "Astrin is required for the maintenance of sister chromatid cohesion and centrosome integrity." in: The Journal of cell biology, Vol. 178, Issue 3, pp. 345-54, (2007) (PubMed).

Synonyme und alternative Namen zu Shugoshin

shugoshin 1 (Sgo1), shugoshin centromeric cohesion 1 (sgo1), shugoshin 1 L homeolog (sgo1.L), shugoshin 1 (SGO1), 3300001M08Rik, C81037, NY-BR-85, SGO, sgo1, Sgo1

Bezeichner auf Proteinebene für Shugoshin

  • AY109536_SNP
  • CL5684_1
  • CL5684_1_ov
  • gnp_AW055587
  • gpm134
  • p-std614083G09
  • shugoshin-1
  • shugoshin-like protein
  • shugosin centromeric cohesion1
  • std614083G09
  • zmSGO1
  • xsgo
  • hSgo1
  • serologically defined breast cancer antigen NY-BR-85
  • shugoshin 1AB protein
  • shugoshin 1CD protein
  • shugoshin 1EF protein
  • shugoshin 1GH protein
  • shugoshin 1KL protein
  • shugoshin-like 1
  • shugoshin 1A protein
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