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SIAH2 Produkte

(Siah E3 Ubiquitin Protein Ligase 2 (SIAH2))
This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in regulating cellular response to hypoxia. [provided by RefSeq, Jul 2008].

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Ausgewählte SIAH2 Kategorien

SIAH2 Antikörper

High quality antibodies with extensive validation data.

SIAH2 ELISA Kits

Reliable ELISA kits for a wide range of species.

SIAH2 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene SIAH2 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, IHC, IF, ICC
Validierungen
  • (4)
Kat. Nr. ABIN6265080
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, IHC, IF
Validierungen
  • (3)
Kat. Nr. ABIN7151218
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, FACS, IHC (p)
Validierungen
  • (3)
Kat. Nr. ABIN652059
Menge 400 μL
Datenblatt Datenblatt

Empfohlene SIAH2 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method
Validierungen
Kat. Nr. ABIN1131322
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method
Validierungen
Kat. Nr. ABIN1131323
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method
Validierungen
Kat. Nr. ABIN1131324
Menge 96 tests
Datenblatt Datenblatt

Empfohlene SIAH2 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1319979
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1319977
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3095363
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren SIAH2 Produkten

Ma, Cheng, Mu, Geng, Zhao, Luo, Ma, Chang, Liu, Gao, Nie, Xie, Han, Chen, Ma, Zhu, Chen: "The SIAH2-NRF1 axis spatially regulates tumor microenvironment remodeling for tumor progression." in: Nature communications, Vol. 10, Issue 1, pp. 1034, (2019) (PubMed).

Hughes, Hemenway, Guo, Yi, Yu, Hawley: "The E3 ubiquitin ligase Sina regulates the assembly and disassembly of the synaptonemal complex in Drosophila females." in: PLoS genetics, Vol. 15, Issue 5, pp. e1008161, (2019) (PubMed).

Jing, Nguyen, Wang, Pascal, Guo, Xu, Ai, Deng, Masoodi, Yu, Zhang, Nelson, Xia, Wang: "DHX15 promotes prostate cancer progression by stimulating Siah2-mediated ubiquitination of androgen receptor." in: Oncogene, Vol. 37, Issue 5, pp. 638-650, (2018) (PubMed).

Ma, Cheng, Gao, Mu, Chen, Wu, Chen, Zhu: "Zyxin-Siah2-Lats2 axis mediates cooperation between Hippo and TGF-β signalling pathways." in: Nature communications, Vol. 7, pp. 11123, (2016) (PubMed).

van der Willik, Timmermans, van Deurzen, Look, Reijm, van Zundert, Foekens, Trapman-Jansen, den Bakker, Westenend, Martens, Berns, Jansen: "SIAH2 protein expression in breast cancer is inversely related with ER status and outcome to tamoxifen therapy." in: American journal of cancer research, Vol. 6, Issue 2, pp. 270-84, (2016) (PubMed).

van Reesema, Zheleva, Winston, Jansen, OConnor, Isbell, Bian, Qin, Bassett, Hinson, Dorsch, Kirby, Van Sciver, Tang-Tan, Harden, Chang, Allen, Perry, Hoefer, Tang: "SIAH and EGFR, Two RAS Pathway Biomarkers, are Highly Prognostic in Locally Advanced and Metastatic Breast Cancer." in: EBioMedicine, Vol. 11, pp. 183-198, (2016) (PubMed).

Tanaka, Li, Urata, Goto, Ono, Kawakatsu, Matsushima, Hirabaru, Adachi, Kitasato, Takatsuki, Kuroki, Eguchi: "Increased expression of PHD3 represses the HIF-1 signaling pathway and contributes to poor neovascularization in pancreatic ductal adenocarcinoma." in: Journal of gastroenterology, Vol. 50, Issue 9, pp. 975-83, (2015) (PubMed).

Qin, Smyrk, Reed, Schmidt, Schnelldorfer, Chari, Petersen, Tang: "Combining clinicopathological predictors and molecular biomarkers in the oncogenic K-RAS/Ki67/HIF-1α pathway to predict survival in resectable pancreatic cancer." in: British journal of cancer, Vol. 112, Issue 3, pp. 514-22, (2015) (PubMed).

Moreno, Lara-Chica, Soler-Torronteras, Caro, Medina, Álvarez, Salvatierra, Muñoz, Calzado: "The Expression of the Ubiquitin Ligase SIAH2 (Seven In Absentia Homolog 2) Is Increased in Human Lung Cancer." in: PLoS ONE, Vol. 10, Issue 11, pp. e0143376, (2015) (PubMed).

Wong, Chen, Liu, Parker, Möller: "Loss of Siah2 does not impact angiogenic potential of murine endothelial cells." in: Microvascular research, Vol. 102, pp. 38-45, (2015) (PubMed).

Synonyme und alternative Namen zu SIAH2

siah E3 ubiquitin protein ligase 2 (SIAH2), siah E3 ubiquitin protein ligase 2 L homeolog (siah2.L), seven in absentia 2 (Siah2), siah E3 ubiquitin protein ligase 2 (Siah2), AA415433, hSiah2, siah2-A, Sinh2, Xsiah-2, xsiah2

Bezeichner auf Proteinebene für SIAH2

  • E3 ubiquitin-protein ligase SIAH2
  • seven in absentia homolog 2
  • siah-2
  • seven in absentia-like protein
  • E3 ubiquitin-protein ligase siah2
  • mSiah2
  • seven in absentia 2
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