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SIGLEC5 Produkte

(Sialic Acid Binding Ig-Like Lectin 5 (SIGLEC5))
This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion. [provided by RefSeq, Feb 2012].

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Ausgewählte SIGLEC5 Kategorien

SIGLEC5 Antikörper

High quality antibodies with extensive validation data.

SIGLEC5 ELISA Kits

Reliable ELISA kits for a wide range of species.

SIGLEC5 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene SIGLEC5 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation ELISA, FACS
Validierungen
  • (4)
Kat. Nr. ABIN7193301
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, ELISA, IHC
Validierungen
  • (3)
Kat. Nr. ABIN7249022
Menge 200 μL
Datenblatt Datenblatt
Reaktivität Human, Non-Human Primate
Applikation FACS
Validierungen
  • (2)
Kat. Nr. ABIN7505866
Menge 100 tests
Datenblatt Datenblatt

Empfohlene SIGLEC5 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN625088
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN5510738
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN5526846
Menge 96 tests
Datenblatt Datenblatt

Empfohlene SIGLEC5 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (2)
Kat. Nr. ABIN7275589
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (2)
Kat. Nr. ABIN7275598
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source HEK-293 Cells
Validierungen
  • (2)
Kat. Nr. ABIN7275613
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren SIGLEC5 Produkten

Suematsu, Miyamoto, Saijo, Yamasaki, Tada, Yoshida, Miyake: "Identification of lipophilic ligands of Siglec5 and -14 that modulate innate immune responses." in: The Journal of biological chemistry, Vol. 294, Issue 45, pp. 16776-16788, (2019) (PubMed).

Huang, Low, Wang, Hsu, Angata: "Soluble Siglec-14 glycan-recognition protein is generated by alternative splicing and suppresses myeloid inflammatory responses." in: The Journal of biological chemistry, Vol. 293, Issue 51, pp. 19645-19658, (2018) (PubMed).

Alkhodair, Almhanna, McGetrick, Gedair, Gallagher, Fernandez-Fuertes, Tharmalingam, Larsen, Fitzpatrick, Lonergan, Evans, Carrington, Reid: "Siglec expression on the surface of human, bull and ram sperm." in: Reproduction (Cambridge, England), Vol. 155, Issue 4, pp. 361-371, (2018) (PubMed).

Wu, Ding, Han, Arriens, Wei, Han, Pedroza, Jiang, Anolik, Petri, Sanz, Saxena, Mohan: "Antibody-Array-Based Proteomic Screening of Serum Markers in Systemic Lupus Erythematosus: A Discovery Study." in: Journal of proteome research, Vol. 15, Issue 7, pp. 2102-14, (2016) (PubMed).

Madge, Maggioni, Pascolutti, Amin, Waespy, Bellette, Thomson, Kelm, von Itzstein, Haselhorst: "Structural characterisation of high affinity Siglec-2 (CD22) ligands in complex with whole Burkitt's lymphoma (BL) Daudi cells by NMR spectroscopy." in: Scientific reports, Vol. 6, pp. 36012, (2016) (PubMed).

Pepin, Mezouar, Pegon, Muczynski, Adam, Bianchini, Bazaa, Proulle, Rupin, Paysant, Panicot-Dubois, Christophe, Dubois, Lenting, Denis: "Soluble Siglec-5 associates to PSGL-1 and displays anti-inflammatory activity." in: Scientific reports, Vol. 6, pp. 37953, (2016) (PubMed).

Ali, Fong, Carlin, Busch, Linden, Angata, Areschoug, Parast, Varki, Murray, Nizet, Varki: "Siglec-5 and Siglec-14 are polymorphic paired receptors that modulate neutrophil and amnion signaling responses to group B Streptococcus." in: The Journal of experimental medicine, Vol. 211, Issue 6, pp. 1231-42, (2014) (PubMed).

Yang, Jiang, Li, Qiu, Zhang, Carter, Al-Quran, Li: "Developing aptamer probes for acute myelogenous leukemia detection and surface protein biomarker discovery." in: Journal of hematology & oncology, Vol. 7, pp. 5, (2014) (PubMed).

Izquierdo-Useros, Lorizate, Puertas, Rodriguez-Plata, Zangger, Erikson, Pino, Erkizia, Glass, Clotet, Keppler, Telenti, Kräusslich, Martinez-Picado: "Siglec-1 is a novel dendritic cell receptor that mediates HIV-1 trans-infection through recognition of viral membrane gangliosides." in: PLoS biology, Vol. 10, Issue 12, pp. e1001448, (2012) (PubMed).

Zou, Chastain, Moir, Ford, Trandem, Martinelli, Cicala, Crocker, Arthos, Sun: "Siglecs facilitate HIV-1 infection of macrophages through adhesion with viral sialic acids." in: PLoS ONE, Vol. 6, Issue 9, pp. e24559, (2011) (PubMed).

Synonyme und alternative Namen zu SIGLEC5

sialic acid binding Ig like lectin 5 (SIGLEC5), sialic acid-binding Ig-like lectin 5 (LOC100597560), sialic acid binding Ig-like lectin 5 (Siglec5), CD33L2, CD170, OB-BP2, OBBP2, SIGLEC-5

Bezeichner auf Proteinebene für SIGLEC5

  • CD33 antigen-like 2
  • OB-binding protein 2
  • obesity-binding protein 2
  • sialic acid-binding Ig-like lectin 5
  • sialic acid-binding immunoglobulin-like lectin 5
  • sialic acid binding Ig-like lectin 5
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