Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

SIGMAR1 Produkte

(sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1))
This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor\; it is now thought to be a non-opioid receptor. Alternative splicing of this gene results in transcript variants encoding distinct isoforms. [provided by RefSeq, Dec 2008].

antibodies-online.com steht für hochwertige Forschungsprodukte. Suchen, finden und bestellen Sie Tools mit umfangreichen Validierungsdaten, Bildern, Referenzen. Unser wissenschaftlicher Kundenservice steht Ihnen jederzeit zur Verfügung, wenn Sie Fragen zur Auswahl oder Anwendung unserer Produkte haben.

Ausgewählte SIGMAR1 Kategorien

SIGMAR1 Antikörper

High quality antibodies with extensive validation data.

SIGMAR1 ELISA Kits

Reliable ELISA kits for a wide range of species.

SIGMAR1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene SIGMAR1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, FACS
Validierungen
  • (1)
  • (3)
Kat. Nr. ABIN389221
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, IHC
Validierungen
  • (2)
Kat. Nr. ABIN7169599
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro)
Validierungen
  • (2)
Kat. Nr. ABIN709841
Menge 100 μL
Datenblatt Datenblatt

Empfohlene SIGMAR1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Cow
Analytical Method Quantitative
Validierungen
Kat. Nr. ABIN1058417
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Dog
Analytical Method Quantitative
Validierungen
Kat. Nr. ABIN1058418
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Chicken
Analytical Method Quantitative
Validierungen
Kat. Nr. ABIN1058419
Menge 96 tests
Datenblatt Datenblatt

Empfohlene SIGMAR1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1790001
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3131913
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3117656
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren SIGMAR1 Produkten

López, Gorantla, Segarra, Andino Norat, Álvarez, Skolasky, Meléndez: "Sigma-1 Receptor Antagonist (BD1047) Decreases Cathepsin B Secretion in HIV-Infected Macrophages Exposed to Cocaine." in: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, (2018) (PubMed).

Ortíz-Rentería, Juárez-Contreras, González-Ramírez, Islas, Sierra-Ramírez, Llorente, Simon, Hiriart, Rosenbaum, Morales-Lázaro: "TRPV1 channels and the progesterone receptor Sig-1R interact to regulate pain." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, Issue 7, pp. E1657-E1666, (2018) (PubMed).

Gueguinou, Crottès, Chantôme, Rapetti-Mauss, Potier-Cartereau, Clarysse, Girault, Fourbon, Jézéquel, Guérin-Charbonnel, Fromont, Martin, Pellissier, Schiappa, Chamorey, Mignen, Uguen, Borgese et al.: "The SigmaR1 chaperone drives breast and colorectal cancer cell migration by tuning SK3-dependent Ca2+ homeostasis. ..." in: Oncogene, Vol. 36, Issue 25, pp. 3640-3647, (2017) (PubMed).

Mishra, Mavlyutov, Singh, Biener, Yang, Oliver, Ruoho, Raicu: "The sigma-1 receptors are present in monomeric and oligomeric forms in living cells in the presence and absence of ligands." in: The Biochemical journal, Vol. 466, Issue 2, pp. 263-71, (2015) (PubMed).

Sun, Kawahara, Nagamune: "Modeling tandem AAG8-MEK inhibition in melanoma cells." in: Cancer medicine, Vol. 3, Issue 3, pp. 710-8, (2014) (PubMed).

Vollrath, Sechi, Dreser, Katona, Wiemuth, Vervoorts, Dohmen, Chandrasekar, Prause, Brauers, Jesse, Weis, Goswami: "Loss of function of the ALS protein SigR1 leads to ER pathology associated with defective autophagy and lipid raft disturbances." in: Cell death & disease, Vol. 5, pp. e1290, (2014) (PubMed).

Kimura, Fujita, Shibata, Mori, Yamashita: "Sigma-1 receptor enhances neurite elongation of cerebellar granule neurons via TrkB signaling." in: PLoS ONE, Vol. 8, Issue 10, pp. e75760, (2013) (PubMed).

Prause, Goswami, Katona, Roos, Schnizler, Bushuven, Dreier, Buchkremer, Johann, Beyer, Deschauer, Troost, Weis: "Altered localization, abnormal modification and loss of function of Sigma receptor-1 in amyotrophic lateral sclerosis." in: Human molecular genetics, Vol. 22, Issue 8, pp. 1581-600, (2013) (PubMed).

Chiabrando, Marro, Mercurio, Giorgi, Petrillo, Vinchi, Fiorito, Fagoonee, Camporeale, Turco, Merlo, Silengo, Altruda, Pinton, Tolosano: "The mitochondrial heme exporter FLVCR1b mediates erythroid differentiation." in: The Journal of clinical investigation, Vol. 122, Issue 12, pp. 4569-79, (2012) (PubMed).

Lee, Chen, Schetz et al.: "An unambiguous assay for the cloned human sigma1 receptor reveals high affinity interactions with dopamine D4 receptor selective compounds and a distinct structure-affinity relationship for ..." in: European journal of pharmacology, Vol. 578, Issue 2-3, pp. 123-36, (2008) (PubMed).

Synonyme und alternative Namen zu SIGMAR1

sigma non-opioid intracellular receptor 1 (SIGMAR1), sigma non-opioid intracellular receptor 1 (Sigmar1), sigma non-opioid intracellular receptor 1 L homeolog (sigmar1.L), sigma non-opioid intracellular receptor 1 (sigmar1), AL024364, ALS16, mSigmaR1, OPRS1, Oprs1, oprs1, SIG-1R, sigma1R, Sigma1R, SR-BP, SR-BP1, SRBP, zgc:56378

Bezeichner auf Proteinebene für SIGMAR1

  • SR31747 binding protein 1
  • aging-associated gene 8 protein
  • hSigmaR1
  • sigma 1-type opioid receptor
  • opioid receptor, sigma 1
  • sigma1-receptor
  • sigma1R
  • Sigma 1-type opioid receptor
  • Sigma1-receptor
  • sigma1-receptor (sterol-isomerase like protein)
  • sterol isomerase-like protein
Sie sind hier:
Kundenservice