SIP1 Produkte
(Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2))
Kategorien
This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration. [provided by RefSeq, Aug 2011].
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Ausgewählte SIP1 Kategorien
SIP1 Antikörper
High quality antibodies with extensive validation data.
SIP1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene SIP1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC, ICC, IHC (p)
Validierungen
- (4)
Kat. Nr.
ABIN625932
Menge
0.05 mg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF, IP
Validierungen
- (3)
Kat. Nr.
ABIN7153753
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF
Validierungen
- (3)
Kat. Nr.
ABIN521936
Menge
50 μg
Datenblatt
Datenblatt
Empfohlene SIP1 ELISA Kits
Produkt
Reaktivität
Analytical Method
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Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6231037
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene SIP1 Proteine
Produkt
Reaktivität
Source
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Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1320025
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3080724
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3128349
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren SIP1 Produkten
: "ZEB2 Represses the Epithelial Phenotype and Facilitates Metastasis in Ewing Sarcoma." in: Genes & cancer, Vol. 4, Issue 11-12, pp. 486-500, (2014) (PubMed).: "JARID2 is involved in transforming growth factor-beta-induced epithelial-mesenchymal transition of lung and colon cancer cell lines." in: PLoS ONE, Vol. 9, Issue 12, pp. e115684, (2014) (PubMed).
: "A novel function for the survival motoneuron protein as a translational regulator." in: Human molecular genetics, Vol. 22, Issue 4, pp. 668-84, (2013) (PubMed).
: "Proteomic assessment of a cell model of spinal muscular atrophy." in: BMC neuroscience, Vol. 12, pp. 25, (2011) (PubMed).
: "GEMIN2 promotes accumulation of RAD51 at double-strand breaks in homologous recombination." in: Nucleic acids research, Vol. 38, Issue 15, pp. 5059-74, (2010) (PubMed).
: "Novel monoclonal antibodies detect Smad-interacting protein 1 (SIP1) in the cytoplasm of human cells from multiple tumor tissue arrays." in: Experimental and molecular pathology, Vol. 89, Issue 2, pp. 182-9, (2010) (PubMed).
: "Regulation of SMN protein stability." in: Molecular and cellular biology, Vol. 29, Issue 5, pp. 1107-15, (2009) (PubMed).
: "SMN complex localizes to the sarcomeric Z-disc and is a proteolytic target of calpain." in: Human molecular genetics, Vol. 17, Issue 21, pp. 3399-410, (2008) (PubMed).
: "A novel cell response triggered by interphase centromere structural instability." in: The Journal of cell biology, Vol. 177, Issue 5, pp. 757-68, (2007) (PubMed).
: "Distinct domains of the spinal muscular atrophy protein SMN are required for targeting to Cajal bodies in mammalian cells." in: Journal of cell science, Vol. 119, Issue Pt 4, pp. 680-92, (2006) (PubMed).
Synonyme und alternative Namen zu SIP1
gem nuclear organelle associated protein 2 (GEMIN2), gem nuclear organelle associated protein 2 (Gemin2), gem (nuclear organelle) associated protein 2 (Gemin2), gem nuclear organelle associated protein 2 S homeolog (gemin2.S), gem (nuclear organelle) associated protein 2 (gemin2), 1700012N19Rik, SIP1, Sip1, sip1, SIP1-delta, sip1-delta, wu:fc52a05, zgc:110274Bezeichner auf Proteinebene für SIP1
- SMN interacting protein 1-delta
- component of gems 2
- gem-associated protein 2
- gemin-2
- survival of motor neuron protein interacting protein 1
- SMN-interacting protein 1
- survival of motor neuron protein-interacting protein 1
- survivor of motor neuron protein interacting protein 1
- SMN interacting protein-1
- Survival of motor neuron protein-interacting protein 1
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