SIRT2 Produkte
(Sirtuin 2 (SIRT2))
Kategorien
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined\; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene. [provided by RefSeq, Jul 2010].
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Ausgewählte SIRT2 Kategorien
SIRT2 Antikörper
High quality antibodies with extensive validation data.
SIRT2 ELISA Kits
Reliable ELISA kits for a wide range of species.
SIRT2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene SIRT2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (6)
Kat. Nr.
ABIN3020852
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF, RNAi
Validierungen
- (5)
Kat. Nr.
ABIN564966
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC (p)
Validierungen
- (6)
Kat. Nr.
ABIN3043924
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene SIRT2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6959488
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6959490
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6959489
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene SIRT2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7125105
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1320041
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN6386645
Menge
50 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren SIRT2 Produkten
: "Identification of serum protein biomarkers for utrophin based DMD therapy." in: Scientific reports, Vol. 7, pp. 43697, (2018) (PubMed).: "The effects of melatonin and curcumin on the expression of SIRT2, Bcl-2 and Bax in the hippocampus of adult rats." in: Brain research bulletin, Vol. 137, pp. 306-310, (2018) (PubMed).
: "The subcellular localization and activity of cortactin is regulated by acetylation and interaction with Keap1." in: Science signaling, Vol. 8, Issue 404, pp. ra120, (2016) (PubMed).
: "Acetylation of Beclin 1 inhibits autophagosome maturation and promotes tumour growth." in: Nature communications, Vol. 6, pp. 7215, (2015) (PubMed).
: "A chromatin modifier genetic screen identifies SIRT2 as a modulator of response to targeted therapies through the regulation of MEK kinase activity." in: Oncogene, Vol. 34, Issue 4, pp. 531-6, (2015) (PubMed).
: "NOTCH-induced aldehyde dehydrogenase 1A1 deacetylation promotes breast cancer stem cells." in: The Journal of clinical investigation, (2014) (PubMed).
: "Effects of niacin restriction on sirtuin and PARP responses to photodamage in human skin." in: PLoS ONE, Vol. 7, Issue 7, pp. e42276, (2012) (PubMed).
: "Alcohol-induced alterations in hepatic microtubule dynamics can be explained by impaired histone deacetylase 6 function." in: Hepatology (Baltimore, Md.), Vol. 48, Issue 5, pp. 1671-9, (2008) (PubMed).
: "Osthole regulates enzyme protein expression of CYP7A1 and DGAT2 via activation of PPARalpha/gamma in fat milk-induced fatty liver rats." in: Journal of Asian natural products research, Vol. 10, Issue 7-8, pp. 807-12, (2008) (PubMed).
: "The regulation of SIRT2 function by cyclin-dependent kinases affects cell motility." in: The Journal of cell biology, Vol. 180, Issue 5, pp. 915-29, (2008) (PubMed).
Synonyme und alternative Namen zu SIRT2
Sirtuin 2 (Sirt2), sirtuin 2 (SIRT2), sirtuin 2 S homeolog (sirt2.S), NAD-dependent deacetylase sirtuin 2 homolog (Sirt2), sirtuin 2 (SRT2), sirtuin 2 (sirt2), sirtuin 2 (Sirt2), sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae) (sirt2), 5730427M03Rik, AtSRT2, BmSirt2, CG5085, D.mel2, Dmel\\CG5085, dSIRT2, sir2, SIR2, SIR2L, Sir2l, SIR2L2, SIRT2, Sirt2, SIRTUIN 2, sirtuin 2, T2K12.8, wu:fb57d05, zgc:55966, zgc:77003Bezeichner auf Proteinebene für SIRT2
- CG5085-PA
- Sirt2-PA
- sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae)
- sirtuin 2
- NAD-dependent deacetylase SIRT2
- NAD-dependent deacetylase sirtuin-2
- histone NADC
- silent information regulator 2
- nicotinamide adenine dinucleotide-dependent histone deacetylase
- NAD-dependent deacetylase sirtuin 2 homolog
- NAD-dependent protein deacetylase sirtuin-2
- SIR2-like protein 2
- regulatory protein SIR2 homolog 2
- sir2-related protein type 2
- sirtuin type 2
- sirtuin-like protein 2
- mSIR2L2
- silent mating type information regulation 2, (S.cerevisiae, homolog)-like; sirtuin 2
- 5E5 antigen
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