SKP1 Produkte
(S-Phase Kinase-Associated Protein 1 (SKP1))
Kategorien
This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Jul 2008].
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Ausgewählte SKP1 Kategorien
SKP1 Antikörper
High quality antibodies with extensive validation data.
SKP1 ELISA Kits
Reliable ELISA kits for a wide range of species.
SKP1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene SKP1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, ICC, FACS
Validierungen
- (1)
- (6)
Kat. Nr.
ABIN969397
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF
Validierungen
- (4)
Kat. Nr.
ABIN562883
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC, IF, ICC
Validierungen
- (4)
Kat. Nr.
ABIN6265102
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene SKP1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6959215
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN1381498
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Cow
Analytical Method
Validierungen
Kat. Nr.
ABIN1156434
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene SKP1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN1320087
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN935072
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1320089
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren SKP1 Produkten
: "A Neonatal Mouse Model for Pressure Overload: Myocardial Response Corresponds to Severity." in: Frontiers in cardiovascular medicine, Vol. 8, pp. 660246, (2021) (PubMed).: "Cyclin F/FBXO1 Interacts with HIV-1 Viral Infectivity Factor (Vif) and Restricts Progeny Virion Infectivity by Ubiquitination and Proteasomal Degradation of Vif Protein through SCFcyclin F E3 Ligase ..." in: The Journal of biological chemistry, Vol. 292, Issue 13, pp. 5349-5363, (2017) (PubMed).
: "Calmodulin protects Aurora B on the midbody to regulate the fidelity of cytokinesis." in: Cell cycle (Georgetown, Tex.), Vol. 12, Issue 4, pp. 663-73, (2013) (PubMed).
: "The myxoma virus m-t5 ankyrin repeat host range protein is a novel adaptor that coordinately links the cellular signaling pathways mediated by Akt and Skp1 in virus-infected cells." in: Journal of virology, Vol. 83, Issue 23, pp. 12068-83, (2009) (PubMed).
: "[Impact of Donor KIR2DS5 Genotype on Outcome Following Haploidentical Hematopoietic Stem Cell Transplantation.]" in: Zhongguo shi yan xue ye xue za zhi / Zhongguo bing li sheng li xue hui = Journal of experimental hematology / Chinese Association of Pathophysiology, Vol. 16, Issue 1, pp. 111-5, (2008) (PubMed).
: "A C-terminal fragment of Cyclin E, generated by caspase-mediated cleavage, is degraded in the absence of a recognizable phosphodegron." in: The Journal of biological chemistry, Vol. 283, Issue 45, pp. 30796-803, (2008) (PubMed).
: "TBP-interacting protein 120B (TIP120B)/cullin-associated and neddylation-dissociated 2 (CAND2) inhibits SCF-dependent ubiquitination of myogenin and accelerates myogenic differentiation." in: The Journal of biological chemistry, Vol. 282, Issue 12, pp. 9017-28, (2007) (PubMed).
: "Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity of the SCF(beta-TrCP1) ubiquitin ligase." in: Molecular cell, Vol. 11, Issue 6, pp. 1445-56, (2003) (PubMed).
: "Perturbation of SUMOlation enzyme Ubc9 by distinct domain within nucleoporin RanBP2/Nup358." in: The Journal of biological chemistry, Vol. 277, Issue 7, pp. 4755-63, (2002) (PubMed).
: "In vivo interference with Skp1 function leads to genetic instability and neoplastic transformation." in: Molecular and cellular biology, Vol. 22, Issue 23, pp. 8375-87, (2002) (PubMed).
Synonyme und alternative Namen zu SKP1
S-phase kinase associated protein 1 (SKP1), S-phase kinase-associated protein 1 (skp1), S-phase kinase-associated protein 1 pseudogene (LOC100340043), S-phase kinase associated protein 1 (skp1), S-phase kinase-associated protein 1A (Skp1a), S-phase kinase-associated protein 1 (Skp1), S-phase kinase-associated protein 1 S homeolog (skp1.S), S-phase kinase-associated protein 1 (SKP1), S phase kinase-associated protein 1 (SKP1), S-phase kinase associated protein 1 (Skp1), 15kDa, 2610043E24Rik, 2610206H23Rik, ARABIDOPSIS SKP1 HOMOLOGUE 1, ASK1, ATSKP1, EMC19, emc19, ocp-2, OCP-II, ocp-ii, OCP2, ocp2, p19A, p19Skp1, SKP1, SKP1A, Skp1a, skp1a, S phase kinase-associated protein 1, T4O12.17, T4O12_17, TCEB1L, Tceb1l, tceb1l, UFO INTERACTING PROTEIN 1, UIP1, zgc:73186Bezeichner auf Proteinebene für SKP1
- OCP-2
- RNA polymerase II elongation factor-like protein OCP2
- SIII
- cyclin A/CDK2-associated p19
- cyclin A/CDK2-associated protein p19
- cyclin-A/CDK2-associated protein p19
- organ of Corti protein 2
- organ of Corti protein II
- p19skp1
- transcription elongation factor B
- S-phase kinase-associated protein 1
- SCF complex component
- S-phase kinase-associated protein 1A
- p19A
- S-phase kinase-associated protein 1A (p19A)
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