SLC12A6 Produkte
(Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 6 (SLC12A6))
Kategorien
This gene is a member of the K-Cl cotransporter (KCC) family. K-Cl cotransporters are integral membrane proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The proteins encoded by this gene are activated by cell swelling induced by hypotonic conditions. Alternate splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are associated with agenesis of the corpus callosum with peripheral neuropathy. [provided by RefSeq, Jul 2008].
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Ausgewählte SLC12A6 Kategorien
SLC12A6 Antikörper
High quality antibodies with extensive validation data.
SLC12A6 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene SLC12A6 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p)
Validierungen
- (2)
Kat. Nr.
ABIN656316
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (4)
- (1)
Kat. Nr.
ABIN564298
Menge
50 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC
Validierungen
- (2)
Kat. Nr.
ABIN238578
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene SLC12A6 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1320131
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7394462
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3118929
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren SLC12A6 Produkten
: "The K-Cl cotransporter KCC3 as an independent prognostic factor in human esophageal squamous cell carcinoma." in: BioMed research international, Vol. 2014, pp. 936401, (2014) (PubMed).: "Potassium-chloride cotransporter 3 interacts with Vav2 to synchronize the cell volume decrease response with cell protrusion dynamics." in: PLoS ONE, Vol. 8, Issue 5, pp. e65294, (2013) (PubMed).
: "Loss of neuronal potassium/chloride cotransporter 3 (KCC3) is responsible for the degenerative phenotype in a conditional mouse model of hereditary motor and sensory neuropathy associated with ..." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 11, pp. 3865-76, (2012) (PubMed).
: "Transit defect of potassium-chloride Co-transporter 3 is a major pathogenic mechanism in hereditary motor and sensory neuropathy with agenesis of the corpus callosum." in: The Journal of biological chemistry, Vol. 286, Issue 32, pp. 28456-65, (2011) (PubMed).
: "HMSN/ACC truncation mutations disrupt brain-type creatine kinase-dependant activation of K+/Cl- co-transporter 3." in: Human molecular genetics, Vol. 17, Issue 17, pp. 2703-11, (2008) (PubMed).
: "Homooligomeric and heterooligomeric associations between K+-Cl- cotransporter isoforms and between K+-Cl- and Na+-K+-Cl- cotransporters." in: The Journal of biological chemistry, Vol. 282, Issue 25, pp. 18083-93, (2007) (PubMed).
Synonyme und alternative Namen zu SLC12A6
solute carrier family 12, member 6 (Slc12a6), solute carrier family 12 member 6 (SLC12A6), 9530023I19Rik, ACCPN, gaxp, Kcc3, KCC3, KCC3A, KCC3BBezeichner auf Proteinebene für SLC12A6
- solute carrier family 12 member 6
- furosemide-sensitive KCl cotransporter 3
- K-Cl cotransporter 3
- electroneutral potassium-chloride cotransporter 3
- potassium chloride cotransporter 3
- potassium chloride cotransporter KCC3a-S3
- potassium-chloride transporter-3a
- potassium-chloride transporter-3b
- solute carrier family 12 (potassium/chloride transporters), member 6
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