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SLC22A12 Produkte

(Solute Carrier Family 22 (Organic Anion/urate Transporter), Member 12 (SLC22A12))

Kategorien

The protein encoded by this gene is a member of the organic anion transporter (OAT) family, and it acts as a urate transporter to regulate urate levels in blood. This protein is an integral membrane protein primarily found in epithelial cells of the proximal tubule of the kidney. An elevated level of serum urate, hyperuricemia, is associated with increased incidences of gout, and mutations in this gene cause renal hypouricemia type 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013].

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Ausgewählte SLC22A12 Kategorien

SLC22A12 Antikörper

High quality antibodies with extensive validation data.

SLC22A12 ELISA Kits

Reliable ELISA kits for a wide range of species.

SLC22A12 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene SLC22A12 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA
Validierungen
  • (2)
  • (3)
Kat. Nr. ABIN530376
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC
Validierungen
  • (3)
Kat. Nr. ABIN7192423
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB
Validierungen
  • (1)
  • (2)
Kat. Nr. ABIN1682756
Menge 100 μg
Datenblatt Datenblatt

Empfohlene SLC22A12 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6959579
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6959580
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6232809
Menge 96 tests
Datenblatt Datenblatt

Empfohlene SLC22A12 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1320195
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1320194
Menge 25 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7406998
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren SLC22A12 Produkten

Liu, Yuan, Zhou, Zhao, Chen, Cheng, Lu, Liu: "Phloretin attenuates hyperuricemia-induced endothelial dysfunction through co-inhibiting inflammation and GLUT9-mediated uric acid uptake." in: Journal of cellular and molecular medicine, Vol. 21, Issue 10, pp. 2553-2562, (2018) (PubMed).

Tan, Farrar, Gaucher, Miner: "Coevolution of URAT1 and Uricase during Primate Evolution: Implications for Serum Urate Homeostasis and Gout." in: Molecular biology and evolution, Vol. 33, Issue 9, pp. 2193-200, (2016) (PubMed).

Yan, Zhang, Huang, Shen, Han: "OIT3 deficiency impairs uric acid reabsorption in renal tubule." in: FEBS letters, Vol. 586, Issue 6, pp. 760-5, (2012) (PubMed).

Roncal-Jimenez, Lanaspa, Rivard, Nakagawa, Sanchez-Lozada, Jalal, Andres-Hernando, Tanabe, Madero, Li, Cicerchi, Mc Fann, Sautin, Johnson: "Sucrose induces fatty liver and pancreatic inflammation in male breeder rats independent of excess energy intake." in: Metabolism: clinical and experimental, Vol. 60, Issue 9, pp. 1259-70, (2011) (PubMed).

Koepsell, Endou: "The SLC22 drug transporter family." in: Pflügers Archiv : European journal of physiology, Vol. 447, Issue 5, pp. 666-76, (2004) (PubMed).

Anzai, Miyazaki, Endou: "[Molecular biology of urate transporter]." in: Seikagaku. The Journal of Japanese Biochemical Society, Vol. 76, Issue 2, pp. 101-10, (2004) (PubMed).

Anzai, Miyazaki, Noshiro, Khamdang, Chairoungdua, Shin, Enomoto, Sakamoto, Hirata, Tomita, Kanai, Endou: "The multivalent PDZ domain-containing protein PDZK1 regulates transport activity of renal urate-anion exchanger URAT1 via its C terminus." in: The Journal of biological chemistry, Vol. 279, Issue 44, pp. 45942-50, (2004) (PubMed).

Tanaka, Itoh, Matsushita, Matsushita, Wakita, Adachi, Nonoguchi, Kitamura, Hosoyamada, Endou, Tomita: "Two male siblings with hereditary renal hypouricemia and exercise-induced ARF." in: American journal of kidney diseases : the official journal of the National Kidney Foundation, Vol. 42, Issue 6, pp. 1287-92, (2003) (PubMed).

Ichida, Hosoyamada, Hisatome, Enomoto, Hikita, Endou, Hosoya: "Clinical and molecular analysis of patients with renal hypouricemia in Japan-influence of URAT1 gene on urinary urate excretion." in: Journal of the American Society of Nephrology : JASN, Vol. 15, Issue 1, pp. 164-73, (2003) (PubMed).

Synonyme und alternative Namen zu SLC22A12

solute carrier family 22 (organic anion/cation transporter), member 12 (Slc22a12), solute carrier family 22 member 12 (SLC22A12), solute carrier family 22 member 12 (Slc22a12), AI987855, OAT4L, Rst, RST, Slc22al2, URAT1

Bezeichner auf Proteinebene für SLC22A12

  • renal-specific transporter
  • solute carrier family 22 (organic cation transporter)-like 2
  • solute carrier family 22 member 12
  • urate anion exchanger 1
  • organic anion transporter 4-like protein
  • solute carrier family 22 (organic anion/cation transporter), member 12
  • urate transporter 1
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