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SLC46A1 Produkte

(Solute Carrier Family 46 (Folate Transporter), Member 1 (SLC46A1))

Kategorien

This gene encodes a transmembrane proton-coupled folate transporter protein that facilitates the movement of folate and antifolate substrates across cell membranes, optimally in acidic pH environments. This protein is also expressed in the brain and choroid plexus where it transports folates into the central nervous system. This protein further functions as a heme transporter in duodenal enterocytes, and potentially in other tissues like liver and kidney. Its localization to the apical membrane or cytoplasm of intestinal cells is modulated by dietary iron levels. Mutations in this gene are associated with autosomal recessive hereditary folate malabsorption (HFM) disease. HFM is characterized by folate deficiency due to reduced intestinal folate absorption and subsequent anemia, hypoimmunoglobulinemia, and recurrent infections. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2011].

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Ausgewählte SLC46A1 Kategorien

SLC46A1 Antikörper

High quality antibodies with extensive validation data.

SLC46A1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene SLC46A1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation ELISA, IHC
Validierungen
  • (1)
Kat. Nr. ABIN7166588
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA
Validierungen
  • (1)
Kat. Nr. ABIN768542
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Dog, Guinea Pig, Hamster, Horse, Human, Monkey, Mouse, Rat
Applikation WB
Validierungen
  • (1)
Kat. Nr. ABIN6741754
Menge 100 μL
Datenblatt Datenblatt

Empfohlene SLC46A1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
Kat. Nr. ABIN1330511
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3117461
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3123723
Menge 1 mg
Datenblatt Datenblatt

Synonyme und alternative Namen zu SLC46A1

solute carrier family 46 member 1 (SLC46A1), solute carrier family 46 (folate transporter), member 1 (slc46a1), solute carrier family 46 member 1 (Slc46a1), solute carrier family 46, member 1 (Slc46a1), 1110002C08Rik, D11Ertd18e, G21, HCP1, PCFT, Pcft, RGD1309472, TRPE

Bezeichner auf Proteinebene für SLC46A1

  • solute carrier family 46, member 1
  • solute carrier family 46 (folate transporter), member 1
  • proton-coupled folate transporter-like
  • heme carrier protein 1
  • proton-coupled folate transporter
  • PCFT/HCP1
  • retinal pigment epithelilum transporter
  • retinal pigment epithelium transporter
  • solute carrier family 46 member 1
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