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SLC7A11 Produkte

(Solute Carrier Family 7, (Cationic Amino Acid Transporter, Y+ System) Member 11 (SLC7A11))
This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. [provided by RefSeq, Sep 2011].

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Ausgewählte SLC7A11 Kategorien

SLC7A11 Antikörper

High quality antibodies with extensive validation data.

SLC7A11 ELISA Kits

Reliable ELISA kits for a wide range of species.

SLC7A11 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene SLC7A11 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation ELISA, IF
Validierungen
  • (10)
Kat. Nr. ABIN190899
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, ELISA, FACS, FM, IP
Validierungen
  • (4)
Kat. Nr. ABIN6655336
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB
Validierungen
  • (4)
Kat. Nr. ABIN7043751
Menge 25 μL
Datenblatt Datenblatt

Empfohlene SLC7A11 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6970357
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6959627
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6959628
Menge 96 tests
Datenblatt Datenblatt

Empfohlene SLC7A11 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (2)
Kat. Nr. ABIN7491739
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1320520
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (1)
Kat. Nr. ABIN7092733
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren SLC7A11 Produkten

Greenwood, McCormick, Gendron, Glaser, Pereira, Maddocks, Sander, Zhang, Koglin, Lythgoe, Årstad, Hochhauser, Witney: "Measurement of Tumor Antioxidant Capacity and Prediction of Chemotherapy Resistance in Preclinical Models of Ovarian Cancer by Positron Emission Tomography." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 25, Issue 8, pp. 2471-2482, (2019) (PubMed).

Isobe, Kataoka, Endo, Moriyama, Okazaki, Tsuchihashi, Katsumata, Yamamoto, Shirakawa, Yoshida, Shimoda, Chiba, Masuko, Hakamata, Kobayashi, Saya, Fukuda, Sano: "Endothelial-Mesenchymal Transition Drives Expression of CD44 Variant and xCT in Pulmonary Hypertension." in: American journal of respiratory cell and molecular biology, (2019) (PubMed).

Ungard, Linher-Melville, Nashed, Sharma, Wen, Singh: "xCT knockdown in human breast cancer cells delays onset of cancer-induced bone pain." in: Molecular pain, Vol. 15, pp. 1744806918822185, (2019) (PubMed).

Li, Chen, Lan, He, Chen, Wang, Liu, Li, Cheng, Liu, Sun, Wan, Chen, Peng, Li, Zhang, Jing, Huang, Wang, Wang, Jiang, Zha, Chen, Zhang: "mTOR-dependent upregulation of xCT blocks melanin synthesis and promotes tumorigenesis." in: Cell death and differentiation, (2019) (PubMed).

Pitman, Alluri, Kristian, Aarnes, Lyng, Riss, Malinen: "Influx rate of 18F-fluoroaminosuberic acid reflects cystine/glutamate antiporter expression in tumour xenografts." in: European journal of nuclear medicine and molecular imaging, Vol. 46, Issue 10, pp. 2190-2198, (2019) (PubMed).

Hoehne, James, Alam, Ronald, Schneider, DSouza, Witney, Andrews, Cropper, Behera, Gowrishankar, Ding, Wyss-Coray, Chin, Biswal, Gambhir: "[18F]FSPG-PET reveals increased cystine/glutamate antiporter (xc-) activity in a mouse model of multiple sclerosis." in: Journal of neuroinflammation, Vol. 15, Issue 1, pp. 55, (2018) (PubMed).

Miladinovic, Ungard, Linher-Melville, Popovic, Singh: "Functional effects of TrkA inhibition on system xC--mediated glutamate release and cancer-induced bone pain." in: Molecular pain, Vol. 14, pp. 1744806918776467, (2018) (PubMed).

Huang, Lin, Chang, Lei, Ho, Liu, Shyu, Hsieh: "RGS4 deficit in prefrontal cortex contributes to the behaviors related to schizophrenia via system xc--mediated glutamatergic dysfunction in mice." in: Theranostics, Vol. 8, Issue 17, pp. 4781-4794, (2018) (PubMed).

Mi, Dixit, Warner, Kennard, Scharf, Kessler, Moore, Consoli, Bown, Eugene, Kang, Harrison: "Altered glutamate clearance in ascorbate deficient mice increases seizure susceptibility and contributes to cognitive impairment in APP/PSEN1 mice." in: Neurobiology of aging, Vol. 71, pp. 241-254, (2018) (PubMed).

Suárez-Pozos, Martínez-Lozada, Méndez-Flores, Guillem, Hernández-Kelly, Castelán, Olivares-Bañuelos, Chi-Castañeda, Najimi, Ortega: "Characterization of the cystine/glutamate antiporter in cultured Bergmann glia cells." in: Neurochemistry international, (2017) (PubMed).

Synonyme und alternative Namen zu SLC7A11

solute carrier family 7 member 11 (SLC7A11), solute carrier family 7, (cationic amino acid transporter, y+ system) member 11 (SLC7A11), solute carrier family 7 member 11 (Slc7a11), solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 (Slc7a11), 9930009M05Rik, AI451155, CCBR1, DKFZp468E122, SLC7A11, sut, xCT

Bezeichner auf Proteinebene für SLC7A11

  • solute carrier family 7, (cationic amino acid transporter, y+ system) member 11
  • cystine/glutamate transporter
  • solute carrier family 7, member 11
  • Cystine/glutamate transporter
  • cystine/glutamate transporter-like
  • solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
  • amino acid transport system xc-
  • calcium channel blocker resistance protein CCBR1
  • solute carrier family 7 member 11
  • solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
  • cysteine/glutamate transporter
  • sodium independent anionic amino acid transport system
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