SLC8A1 Produkte
(Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 1 (SLC8A1))
Kategorien
In cardiac myocytes, Ca(2+) concentrations alternate between high levels during contraction and low levels during relaxation. The increase in Ca(2+) concentration during contraction is primarily due to release of Ca(2+) from intracellular stores. However, some Ca(2+) also enters the cell through the sarcolemma (plasma membrane). During relaxation, Ca(2+) is sequestered within the intracellular stores. To prevent overloading of intracellular stores, the Ca(2+) that entered across the sarcolemma must be extruded from the cell. The Na(+)-Ca(2+) exchanger is the primary mechanism by which the Ca(2+) is extruded from the cell during relaxation. In the heart, the exchanger may play a key role in digitalis action. The exchanger is the dominant mechanism in returning the cardiac myocyte to its resting state following excitation.[supplied by OMIM, Apr 2004].
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Ausgewählte SLC8A1 Kategorien
SLC8A1 Antikörper
High quality antibodies with extensive validation data.
SLC8A1 ELISA Kits
Reliable ELISA kits for a wide range of species.
Empfohlene SLC8A1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC
Validierungen
- (5)
Kat. Nr.
ABIN6148050
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, FACS, IHC (p)
Validierungen
- (3)
Kat. Nr.
ABIN652886
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC, IF
Validierungen
- (3)
Kat. Nr.
ABIN7043754
Menge
25 μL
Datenblatt
Datenblatt
Empfohlene SLC8A1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6970358
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN5595099
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Competition ELISA
Validierungen
Kat. Nr.
ABIN809058
Menge
96 tests
Datenblatt
Datenblatt
Neueste Publikationen zu unseren SLC8A1 Produkten
: "Effectiveness of gene delivery systems for pluripotent and differentiated cells." in: Molecular therapy. Methods & clinical development, Vol. 2, pp. 14067, (2015) (PubMed).: "Small-molecule activation of SERCA2a SUMOylation for the treatment of heart failure." in: Nature communications, Vol. 6, pp. 7229, (2015) (PubMed).
: "Arrhythmogenic coupling between the Na+ -Ca2+ exchanger and inositol 1,4,5-triphosphate receptor in rat pulmonary vein cardiomyocytes." in: Journal of molecular and cellular cardiology, Vol. 52, Issue 5, pp. 988-97, (2012) (PubMed).
: "Inverse correlation between the extent of N-glycan branching and intercellular adhesion in epithelia. Contribution of the Na,K-ATPase beta1 subunit." in: The Journal of biological chemistry, Vol. 283, Issue 4, pp. 2192-202, (2008) (PubMed).
: "Na+/Ca2+ exchange inhibition protects the rat heart from ischemia-reperfusion injury by blocking energy-wasting processes." in: American journal of physiology. Heart and circulatory physiology, Vol. 288, Issue 4, pp. H1699-707, (2005) (PubMed).
: "Cleavage of the plasma membrane Na+/Ca2+ exchanger in excitotoxicity." in: Cell, Vol. 120, Issue 2, pp. 275-85, (2005) (PubMed).
: "Neurodegeneration: cellular defences destroyed." in: Nature, Vol. 433, Issue 7027, pp. 696-8, (2005) (PubMed).
: "Dietary calcium deficiency increases Ca2+ uptake and Ca2+ extrusion mechanisms in chick enterocytes." in: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, Vol. 139, Issue 2, pp. 133-41, (2004) (PubMed).
: "Cardiac neuronal nitric oxide synthase isoform regulates myocardial contraction and calcium handling." in: Circulation research, Vol. 92, Issue 5, pp. e52-9, (2003) (PubMed).
: "Regulation of phosphatidylinositol-4,5-biphosphate bound to the bovine cardiac Na+/Ca2+ exchanger." in: Annals of the New York Academy of Sciences, Vol. 976, pp. 288-99, (2002) (PubMed).
Synonyme und alternative Namen zu SLC8A1
solute carrier family 8 member A1 (SLC8A1), solute carrier family 8 (sodium/calcium exchanger), member 1 (Slc8a1), solute carrier family 8 member A1 (Slc8a1), solute carrier family 8 (sodium/calcium exchanger), member 1b (slc8a1b), sodium/calcium exchanger 1 (Tsp_07038), AI852629, AV344025, D930008O12Rik, Ncx, NCX1, Ncx1, ncx1n, SLC8A1Bezeichner auf Proteinebene für SLC8A1
- Na(+)/Ca(2+)-exchange protein 1
- Na+/Ca++ exchanger
- Na+/Ca2+ exchanger
- sodium/calcium exchanger 1
- Na/Ca exchanger
- sodium/calcium exchanger isoform NaCa7
- Na-Ca exchanger
- solute carrier family 8, member 1
- sodium-calcium exchanger
- solute carrier family 8 (sodium/calcium exchanger), member 1
- ncx1b
- sodium calcium exchanger 1n
- sodium/calcium exchanger
- sodium/calcium exchanger 1-like
- sodium/calcium exchanger isoform NaCa13
- sodium/calcium exchanger isoform NaCa3
- sodium/calcium exchanger isoform NaCa9
- solute carrier family 8 member 1
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