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SLC9A4 Produkte

(Solute Carrier Family 9 (Sodium/hydrogen Exchanger), Member 4 (SLC9A4))
Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction. May play a specialized role in the kidney in rectifying cell volume in response to extreme fluctuations of hyperosmolar-stimulated cell shrinkage. Is relatively amiloride and ethylisopropylamiloride (EIPA) insensitive. Can be activated under conditions of hyperosmolar-induced cell shrinkage in a sustained intracellular acidification-dependence manner. Activated by 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid (DIDS) in a sustained intracellular acidification-dependence manner. Affects potassium/proton exchange as well as sodium/proton and lithium/proton exchange. In basolateral cell membrane, participates in homeostatic control of intracellular pH, and may play a role in proton extrusion in order to achieve transepithelial HCO3(-) secretion. In apical cell membrane may be involved in mediating sodium absorption. Requires for normal levels of gastric acid secretion, secretory membrane development, parietal cell maturation and/or differentiation and at least secondarily for chief cell differentiation.

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Ausgewählte SLC9A4 Kategorien

SLC9A4 Antikörper

High quality antibodies with extensive validation data.

SLC9A4 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene SLC9A4 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Rat
Applikation ELISA, WB
Validierungen
Kat. Nr. ABIN3172632
Menge 100 μg
Datenblatt Datenblatt

Empfohlene SLC9A4 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3115604
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3136272
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren SLC9A4 Produkten

Hadsell, Hadsell, Rijnkels, Carcamo-Bahena, Wei, Williamson, Grusak: "In silico mapping of quantitative trait loci (QTL) regulating the milk ionome in mice identifies a milk iron locus on chromosome 1." in: Mammalian genome : official journal of the International Mammalian Genome Society, Vol. 29, Issue 9-10, pp. 632-655, (2019) (PubMed).

Synonyme und alternative Namen zu SLC9A4

solute carrier family 9 member A4 (SLC9A4), solute carrier family 9 member A4 (slc9a4), solute carrier family 9 (sodium/hydrogen exchanger), member 4 (Slc9a4), solute carrier family 9 member A4 (Slc9a4), AW990558, D730009J23Rik, NHE4, Nhe4, SLC9A2

Bezeichner auf Proteinebene für SLC9A4

  • solute carrier family 9 (sodium/hydrogen exchanger), member 4
  • Na+/H+ exchanger
  • solute carrier family 9 (sodium/hydrogen exchanger), member 2
  • sodium/hydrogen exchanger 4-like
  • NHE-4
  • Na(+)/H(+) exchanger 4
  • sodium/hydrogen exchanger 4
  • solute carrier family 9 member 4
  • solute carrier family 9 (sodium/hydrogen exchanger)
  • Solute carrier family 9 (sodium/hydrogen exchanger)
  • solute carrier family 9 (sodium/hydrogen exchanger) isoform 4
  • solute carrier family 9, member 4
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