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SMARCA4 Produkte

(SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 (SMARCA4))
The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012].

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Ausgewählte SMARCA4 Kategorien

SMARCA4 Antikörper

High quality antibodies with extensive validation data.

SMARCA4 ELISA Kits

Reliable ELISA kits for a wide range of species.

SMARCA4 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene SMARCA4 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, IF, IHC (p), CUT&RUN
Validierungen
  • (2)
  • (1)
Kat. Nr. ABIN6991990
Menge 0.1 mg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IF, IP
Validierungen
  • (5)
Kat. Nr. ABIN3022959
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, IF, IP
Validierungen
  • (6)
Kat. Nr. ABIN2451926
Menge 100 μg
Datenblatt Datenblatt

Empfohlene SMARCA4 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6975082
Menge 96 tests
Datenblatt Datenblatt

Empfohlene SMARCA4 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1320623
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (2)
Kat. Nr. ABIN2669726
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN2131870
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren SMARCA4 Produkten

Zhang, Geng, Liu, Li, Gao, Liu, Fang, Chang: "Celastrol ameliorates liver metabolic damage caused by a high-fat diet through Sirt1." in: Molecular metabolism, Vol. 6, Issue 1, pp. 138-147, (2018) (PubMed).

Singh, Foley, Rubino, Boyle, Tandon, Shah, Archer: "Brg1 Enables Rapid Growth of the Early Embryo by Suppressing Genes That Regulate Apoptosis and Cell Growth Arrest." in: Molecular and cellular biology, Vol. 36, Issue 15, pp. 1990-2010, (2016) (PubMed).

Chen, Han, Wei, Zhang, Shi, Duan, Li, Zhou, Pu, Zhang, Kang: "SNORD76, a box C/D snoRNA, acts as a tumor suppressor in glioblastoma." in: Scientific reports, Vol. 5, pp. 8588, (2015) (PubMed).

Jelinic, Schlappe, Conlon, Tseng, Olvera, Dao, Mueller, Hussein, Soslow, Levine: "Concomitant loss of SMARCA2 and SMARCA4 expression in small cell carcinoma of the ovary, hypercalcemic type." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 29, Issue 1, pp. 60-6, (2015) (PubMed).

Singh, Archer: "Analysis of the SWI/SNF chromatin-remodeling complex during early heart development and BAF250a repression cardiac gene transcription during P19 cell differentiation." in: Nucleic acids research, Vol. 42, Issue 5, pp. 2958-75, (2014) (PubMed).

Miyamoto, Pasque, Jullien, Gurdon: "Nuclear actin polymerization is required for transcriptional reprogramming of Oct4 by oocytes." in: Genes & development, Vol. 25, Issue 9, pp. 946-58, (2011) (PubMed).

Goldman, Garlick, Kingston: "Chromatin remodeling by imitation switch (ISWI) class ATP-dependent remodelers is stimulated by histone variant H2A.Z." in: The Journal of biological chemistry, Vol. 285, Issue 7, pp. 4645-51, (2010) (PubMed).

Ohkawa, Harada, Nakamura, Yoshimura, Tachibana: "Production of a rat monoclonal antibody against Brg1." in: Hybridoma (2005), Vol. 28, Issue 6, pp. 463-6, (2009) (PubMed).

de la Serna, Ohkawa, Higashi, Dutta, Osias, Kommajosyula, Tachibana, Imbalzano: "The microphthalmia-associated transcription factor requires SWI/SNF enzymes to activate melanocyte-specific genes." in: The Journal of biological chemistry, Vol. 281, Issue 29, pp. 20233-41, (2006) (PubMed).

Synonyme und alternative Namen zu SMARCA4

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 (SMARCA4), SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 (Smarca4), b2b692Clo, BAF190, BAF190A, brg-1, BRG1, Brg1, HP1-BP72, hSNF2b, MRD16, RTPS2, SMARCA4, SNF2, SNF2beta, SNF2L4, SNF2LB, SW1/SNF, SWI2

Bezeichner auf Proteinebene für SMARCA4

  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
  • SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4
  • transcription activator BRG1-like
  • ATP-dependent helicase SMARCA4
  • BRG1-associated factor 190A
  • BRM/SWI2-related gene 1
  • SNF2-beta
  • SNF2-like 4
  • brahma protein-like 1
  • global transcription activator homologous sequence
  • homeotic gene regulator
  • mitotic growth and transcription activator
  • nuclear protein GRB1
  • protein BRG-1
  • protein brahma homolog 1
  • sucrose nonfermenting-like 4
  • transcription activator BRG1
  • BAF190A
  • SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4
  • SWI/SNF related transcriptional activator
  • WI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
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