SMG1 Produkte
(pi-3-Kinase-Related Kinase SMG-1 (SMG1))
Kategorien
This gene encodes a protein involved in nonsense-mediated mRNA decay (NMD) as part of the mRNA surveillance complex. The protein has kinase activity and is thought to function in NMD by phosphorylating the regulator of nonsense transcripts 1 protein. Alternatively spliced transcript variants have been described, but their full-length nature has yet to be determined. [provided by RefSeq, Mar 2013].
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Ausgewählte SMG1 Kategorien
SMG1 Antikörper
High quality antibodies with extensive validation data.
SMG1 ELISA Kits
Reliable ELISA kits for a wide range of species.
Empfohlene SMG1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
ELISA, WB, IHC (p)
Validierungen
- (2)
- (4)
Kat. Nr.
ABIN524936
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, WB, IHC (p)
Validierungen
- (4)
Kat. Nr.
ABIN524937
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, WB, IF
Validierungen
- (3)
Kat. Nr.
ABIN564996
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene SMG1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Validierungen
Kat. Nr.
ABIN1157385
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Validierungen
Kat. Nr.
ABIN1157386
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene SMG1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1320674
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren SMG1 Produkten
: "Downregulation of SMG-1 in HPV-positive head and neck squamous cell carcinoma due to promoter hypermethylation correlates with improved survival." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 18, Issue 5, pp. 1257-67, (2012) (PubMed).: "The nonsense-mediated mRNA decay SMG-1 kinase is regulated by large-scale conformational changes controlled by SMG-8." in: Genes & development, Vol. 25, Issue 2, pp. 153-64, (2011) (PubMed).
: "Post-transcriptional defects of antioxidant selenoenzymes cause oxidative stress under methylmercury exposure." in: The Journal of biological chemistry, Vol. 286, Issue 8, pp. 6641-9, (2011) (PubMed).
: "Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly." in: The Journal of biological chemistry, Vol. 285, Issue 26, pp. 20109-16, (2010) (PubMed).
: "Smg1 is required for embryogenesis and regulates diverse genes via alternative splicing coupled to nonsense-mediated mRNA decay." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 27, pp. 12186-91, (2010) (PubMed).
: "Processing bodies are not required for mammalian nonsense-mediated mRNA decay." in: RNA (New York, N.Y.), Vol. 15, Issue 7, pp. 1265-73, (2009) (PubMed).
: "Circadian oscillation of nucleotide excision repair in mammalian brain." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 8, pp. 2864-7, (2009) (PubMed).
: "The mRNA surveillance protein hSMG-1 functions in genotoxic stress response pathways in mammalian cells." in: Molecular cell, Vol. 14, Issue 5, pp. 585-98, (2004) (PubMed).
: "The ATM-related kinase, hSMG-1, bridges genome and RNA surveillance pathways." in: DNA repair, Vol. 3, Issue 8-9, pp. 919-25, (2004) (PubMed).
: "Phosphoinositide 3-kinase signalling pathways." in: Journal of cell science, Vol. 114, Issue Pt 8, pp. 1439-45, (2001) (PubMed).
Synonyme und alternative Namen zu SMG1
SMG1, nonsense mediated mRNA decay associated PI3K related kinase (SMG1), SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans) (Smg1), SMG1 phosphatidylinositol 3-kinase-related kinase (smg1), Serine/threonine-protein kinase smg-1 (smg-1), 61E3.4, 2610207I05Rik, 5430435M13Rik, ATX, C130002K18Rik, LIP, mKIAA0421, zgc:152973Bezeichner auf Proteinebene für SMG1
- PI-3-kinase-related kinase SMG-1
- lambda-interacting protein
- lambda/iota protein kinase C-interacting protein
- serine/threonine-protein kinase SMG1
- smg-1 homolog, phosphatidylinositol 3-kinase-related kinase
- SMG-1
- phosphatidylinositol 3-kinase-related protein kinase
- SMG1 homolog, phosphatidylinositol 3-kinase-related kinase
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