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SNAP23 Produkte

(Synaptosomal-Associated Protein, 23kDa (SNAP23))

Kategorien

Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-associated protein of 25 kDa), form a complex which serves as a binding site for the general membrane fusion machinery. Synaptobrevin/VAMP and syntaxin are believed to be involved in vesicular transport in most, if not all cells, while SNAP25 is present almost exclusively in the brain, suggesting that a ubiquitously expressed homolog of SNAP25 exists to facilitate transport vesicle/target membrane fusion in other tissues. The protein encoded by this gene is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternative transcript variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008].

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Ausgewählte SNAP23 Kategorien

SNAP23 Antikörper

High quality antibodies with extensive validation data.

SNAP23 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene SNAP23 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (7)
Kat. Nr. ABIN7444214
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Mouse
Applikation WB, IHC, IP, ICC
Validierungen
  • (7)
Kat. Nr. ABIN7444226
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IP, IHC (p)
Validierungen
  • (5)
Kat. Nr. ABIN563782
Menge 100 μg
Datenblatt Datenblatt

Empfohlene SNAP23 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6221616
Menge 96 tests
Datenblatt Datenblatt

Empfohlene SNAP23 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1320745
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN934997
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7505232
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren SNAP23 Produkten

Tadokoro, Shibata, Inoh, Amano, Nakanishi, Hirashima, Utsunomiya-Tate: "Phosphorylation of syntaxin-3 at Thr 14 negatively regulates exocytosis in RBL-2H3 mast cells." in: Cell biology international, Vol. 40, Issue 5, pp. 589-96, (2016) (PubMed).

Martineau, Shi, Puyal, Knolhoff, Dulong, Gasnier, Klingauf, Sweedler, Jahn, Mothet: "Storage and uptake of D-serine into astrocytic synaptic-like vesicles specify gliotransmission." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 8, pp. 3413-23, (2013) (PubMed).

Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).

Stadler, Hjelmare, Neumann, Jonasson, Pepperkok, Uhlén, Lundberg: "Systematic validation of antibody binding and protein subcellular localization using siRNA and confocal microscopy." in: Journal of proteomics, Vol. 75, Issue 7, pp. 2236-51, (2012) (PubMed).

Boström, Andersson, Vind, Håversen, Rutberg, Wickström, Larsson, Jansson, Svensson, Brånemark, Ling, Beck-Nielsen, Borén, Højlund, Olofsson: "The SNARE protein SNAP23 and the SNARE-interacting protein Munc18c in human skeletal muscle are implicated in insulin resistance/type 2 diabetes." in: Diabetes, Vol. 59, Issue 8, pp. 1870-8, (2010) (PubMed).

Gratacòs, Costas, de Cid, Bayés, González, Baca-García, de Diego, Fernández-Aranda, Fernández-Piqueras, Guitart, Martín-Santos, Martorell, Menchón, Roca, Sáiz-Ruiz, Sanjuán, Torrens, Urretavizcaya et al.: "Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and ..." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 150B, Issue 6, pp. 808-16, (2009) (PubMed).

Synonyme und alternative Namen zu SNAP23

synaptosome associated protein 23 (SNAP23), synaptosome associated protein 23kDa (snap23), synaptosomal-associated protein 23 (Snap23), synaptosome associated protein 23 (Snap23), synaptosome associated protein 23kDa L homeolog (snap23.L), 23kDa, AA408749, HsT17016, SNAP-23, snap23-A, SNAP23A, SNAP23B, Sndt, Syndet, XOSNAP-23

Bezeichner auf Proteinebene für SNAP23

  • synaptosomal-associated protein 23
  • synaptosomal-associated protein 23 isoform SNAP23A
  • synaptosomal-associated protein, 23kDa
  • synaptosomal-associated protein, 23kD
  • vesicle-membrane fusion protein SNAP-23
  • SNAP-23
  • synaptosomal-associated protein 23 kD
  • synaptosomal-associated protein, 23 kD
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