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SNCA Produkte

(Synuclein, alpha (SNCA))

Kategorien

Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq, Mar 2009].

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Ausgewählte SNCA Kategorien

SNCA Antikörper

High quality antibodies with extensive validation data.

SNCA ELISA Kits

Reliable ELISA kits for a wide range of species.

SNCA Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene SNCA Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, IHC, IF, ICC
Validierungen
  • (7)
Kat. Nr. ABIN6254965
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IF
Validierungen
  • (1)
  • (4)
Kat. Nr. ABIN6148190
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, IHC, IF, ICC
Validierungen
  • (5)
Kat. Nr. ABIN5650939
Menge 100 μL
Datenblatt Datenblatt

Empfohlene SNCA ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (2)
  • (1)
Kat. Nr. ABIN6962177
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (5)
  • (1)
Kat. Nr. ABIN6959829
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (3)
  • (1)
Kat. Nr. ABIN6959830
Menge 96 tests
Datenblatt Datenblatt

Empfohlene SNCA Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (6)
Kat. Nr. ABIN6952303
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Escherichia coli (E. coli)
Validierungen
  • (9)
Kat. Nr. ABIN5651245
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (10)
Kat. Nr. ABIN5065829
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren SNCA Produkten

Mishra, Krishnamurthy: "Neurorestorative effects of sub-chronic administration of ambroxol in rodent model of Parkinson's disease." in: Naunyn-Schmiedeberg's archives of pharmacology, Vol. 393, Issue 3, pp. 429-444, (2021) (PubMed).

Motawi, Sadik, Hamed, Ali, Khalil, Ahmed: "Potential therapeutic effects of antagonizing adenosine A2A receptor, curcumin and niacin in rotenone-induced Parkinson's disease mice model." in: Molecular and cellular biochemistry, Vol. 465, Issue 1-2, pp. 89-102, (2020) (PubMed).

Bhattamisra, Shak, Xi, Safian, Choudhury, Lim, Shahzad, Alhakamy, Anwer, Radhakrishnan, Md: "Nose to brain delivery of rotigotine loaded chitosan nanoparticles in human SH-SY5Y neuroblastoma cells and animal model of Parkinson's disease." in: International journal of pharmaceutics, Vol. 579, pp. 119148, (2020) (PubMed).

Alarcón-Arís, Pavia-Collado, Miquel-Rio, Coppola-Segovia, Ferrés-Coy, Ruiz-Bronchal, Galofré, Paz, Campa, Revilla, Montefeltro, Kordower, Vila, Artigas, Bortolozzi: "Anti-α-synuclein ASO delivered to monoamine neurons prevents α-synuclein accumulation in a Parkinson's disease-like mouse model and in monkeys." in: EBioMedicine, Vol. 59, pp. 102944, (2020) (PubMed).

Han, Xiong, Guo, Huang, Ma, Liu, Xia, Shen, Li, Jiang, Wang, Guo, Xu, Zhang, Liu, Cao, Zhang, Lin, Wang: "Exosomes from patients with Parkinson's disease are pathological in mice." in: Journal of molecular medicine (Berlin, Germany), Vol. 97, Issue 9, pp. 1329-1344, (2020) (PubMed).

Mishra, Chandravanshi, Trigun, Krishnamurthy: "Ambroxol modulates 6-Hydroxydopamine-induced temporal reduction in Glucocerebrosidase (GCase) enzymatic activity and Parkinson's disease symptoms." in: Biochemical pharmacology, Vol. 155, pp. 479-493, (2019) (PubMed).

Akerman, Hossain, Shobo, Zhong, Jourdain, Hancock, George, Breton, Multhaup: "Neurodegenerative Disease-Related Proteins within the Epidermal Layer of the Human Skin." in: Journal of Alzheimer's disease : JAD, Vol. 69, Issue 2, pp. 463-478, (2019) (PubMed).

Lv, Du, Liu, Zhou, Zhang, Zhang: "Rosmarinic acid attenuates inflammatory responses through inhibiting HMGB1/TLR4/NF-κB signaling pathway in a mouse model of Parkinson's disease." in: Life sciences, Vol. 223, pp. 158-165, (2019) (PubMed).

Wi, Lee, Kim, Park, Cho: "An Enriched Environment Ameliorates Oxidative Stress and Olfactory Dysfunction in Parkinson's Disease with α-Synucleinopathy." in: Cell transplantation, Vol. 27, Issue 5, pp. 831-839, (2019) (PubMed).

Zhu, Dou, Wang, Jiang, Wang, Cheng: "Apelin-36 mitigates MPTP/MPP+-induced neurotoxicity: Involvement of α-synuclein and endoplasmic reticulum stress." in: Brain research, Vol. 1721, pp. 146334, (2019) (PubMed).

Synonyme und alternative Namen zu SNCA

synuclein alpha L homeolog (snca.L), alpha-synuclein (LOC619283), synuclein alpha (SNCA), synuclein, alpha (Snca), synuclein alpha (Snca), alphaSYN, LOC619283, MGC64356, NACP, PARK1, PARK4, PD1, snca

Bezeichner auf Proteinebene für SNCA

  • synuclein, alpha
  • alpha-synuclein
  • alpha SYN
  • non-A beta component of AD amyloid
  • non-A4 component of amyloid
  • non A-beta component of AD amyloid
  • synuclein alpha-140
  • alpha synuclein
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