SOCS1 Produkte
(Suppressor of Cytokine Signaling 1 (SOCS1))
Kategorien
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. [provided by RefSeq, Jul 2008].
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Ausgewählte SOCS1 Kategorien
SOCS1 Antikörper
High quality antibodies with extensive validation data.
SOCS1 ELISA Kits
Reliable ELISA kits for a wide range of species.
SOCS1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene SOCS1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (2)
- (6)
Kat. Nr.
ABIN6148263
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
ELISA, IHC, IF, FACS
Validierungen
- (11)
Kat. Nr.
ABIN184575
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Mouse, Rat
Applikation
WB, IF, IHC (p), FACS
Validierungen
- (5)
Kat. Nr.
ABIN652738
Menge
400 μL
Datenblatt
Datenblatt
Empfohlene SOCS1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6959764
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6970479
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6970477
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene SOCS1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7125254
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7125253
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3131672
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren SOCS1 Produkten
: "Poor stimulation of bovine dendritic cells by Mycobacterium bovis culture supernatant and surface extract is associated with decreased activation of ERK and NF-κB and higher expression of SOCS1 and 3." in: Innate immunity, Vol. 26, Issue 6, pp. 537-546, (2020) (PubMed).: "Corilagin Counteracts IL-13Rα1 Signaling Pathway in Macrophages to Mitigate Schistosome Egg-Induced Hepatic Fibrosis." in: Frontiers in cellular and infection microbiology, Vol. 7, pp. 443, (2018) (PubMed).
: "Role of the JAK2/STAT3 signaling pathway in the pathogenesis of type 2 diabetes mellitus with macrovascular complications." in: Oncotarget, Vol. 8, Issue 57, pp. 96958-96969, (2017) (PubMed).
: "Mechanism of Corilagin interference with IL-13/STAT6 signaling pathways in hepatic alternative activation macrophages in schistosomiasis-induced liver fibrosis in mouse model." in: European journal of pharmacology, Vol. 793, pp. 119-126, (2017) (PubMed).
: "MicroRNA-155 may be involved in the pathogenesis of atopic dermatitis by modulating the differentiation and function of T helper type 17 (Th17) cells." in: Clinical and experimental immunology, Vol. 181, Issue 1, pp. 142-9, (2015) (PubMed).
: "TLR7 is a key regulator of innate immunity against Japanese encephalitis virus infection." in: Neurobiology of disease, Vol. 69, pp. 235-47, (2014) (PubMed).
: "The helicase HAGE prevents interferon-α-induced PML expression in ABCB5+ malignant melanoma-initiating cells by promoting the expression of SOCS1." in: Cell death & disease, Vol. 5, pp. e1061, (2014) (PubMed).
: "SOCS-1 mediates ubiquitylation and degradation of GM-CSF receptor." in: PLoS ONE, Vol. 8, Issue 9, pp. e76370, (2013) (PubMed).
: "IL-7 engages multiple mechanisms to overcome chronic viral infection and limit organ pathology." in: Cell, Vol. 144, Issue 4, pp. 601-13, (2011) (PubMed).
: "Loss of JAK2 regulation via a heterodimeric VHL-SOCS1 E3 ubiquitin ligase underlies Chuvash polycythemia." in: Nature medicine, Vol. 17, Issue 7, pp. 845-53, (2011) (PubMed).
Synonyme und alternative Namen zu SOCS1
suppressor of cytokine signaling 1a (socs1a), suppressor of cytokine signaling 1 (socs1), suppressor of cytokine signaling 1 (SOCS1), suppressor of cytokine signaling 1 L homeolog (socs1.L), suppressor of cytokine signaling 1 (Socs1), cis1, CIS1, cish1, CISH1, Cish1, Cish7, jab, JAB, LOC100228306, socs-1, SOCS-1, Socs-1, socs1, SOCS1, socs1b, ssi-1, SSI-1, ssi1, SSI1, tip3, TIP3, zgc:91868Bezeichner auf Proteinebene für SOCS1
- suppressor of cytokine signaling 1
- suppressor of cytokine signalling
- suppressor of cytokine signaling 1b
- suppressor of cytokine signaling 1-like protein
- JAK binding protein
- JAK-binding protein
- STAT induced SH3 protein 1
- STAT-induced STAT inhibitor 1
- TIP-3
- Tec-interacting protein 3
- cytokine-inducible SH2 protein 1
- JAK2-binding protein
- cytokine inducible SH2-containing protein 1
- cytokine inducible SH2-containing protein 7
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