SOS1 Produkte
(Son of Sevenless Homolog 1 (SOS1))
Kategorien
This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4. [provided by RefSeq, Jul 2008].
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Ausgewählte SOS1 Kategorien
SOS1 Antikörper
High quality antibodies with extensive validation data.
SOS1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene SOS1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF, IHC
Validierungen
- (4)
Kat. Nr.
ABIN7170318
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, PLA
Validierungen
- (4)
Kat. Nr.
ABIN520376
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Dog, Human, Mouse, Rat
Applikation
WB, IF, IP, IHC
Validierungen
- (5)
- (2)
Kat. Nr.
ABIN967741
Menge
150 μg
Datenblatt
Datenblatt
Empfohlene SOS1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6970366
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene SOS1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1320973
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3095504
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3135535
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren SOS1 Produkten
: "Phosphoinositide lipid phosphatases: natural regulators of phosphoinositide 3-kinase signaling in T lymphocytes." in: The Journal of biological chemistry, Vol. 283, Issue 5, pp. 2465-9, (2008) (PubMed).: "GEFs in growth factor signaling." in: Growth factors (Chur, Switzerland), Vol. 25, Issue 5, pp. 355-61, (2008) (PubMed).
: "Structural basis of the differential binding of the SH3 domains of Grb2 adaptor to the guanine nucleotide exchange factor Sos1." in: Archives of biochemistry and biophysics, Vol. 479, Issue 1, pp. 52-62, (2008) (PubMed).
: "Effects of SHIP-1 on MMP2 secretion and invasion of SR3Y1 cells." in: Journal of genetics and genomics = Yi chuan xue bao, Vol. 34, Issue 4, pp. 285-93, (2007) (PubMed).
: "T cell-specific deletion of the inositol phosphatase SHIP reveals its role in regulating Th1/Th2 and cytotoxic responses." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 27, pp. 11382-7, (2007) (PubMed).
: "Light Chain 3 associates with a Sos1 guanine nucleotide exchange factor: its significance in the Sos1-mediated Rac1 signaling leading to membrane ruffling." in: Oncogene, Vol. 21, Issue 46, pp. 7060-6, (2002) (PubMed).
: "Chronic myelogenous leukemia blast cell proliferation is inhibited by peptides that disrupt Grb2-SoS complexes." in: Blood, Vol. 98, Issue 6, pp. 1773-81, (2001) (PubMed).
: "ZAP-70 is essential for the T cell antigen receptor-induced plasma membrane targeting of SOS and Vav in T cells." in: The Journal of biological chemistry, Vol. 275, Issue 8, pp. 5966-75, (2000) (PubMed).
: "Signaling from Ras to Rac and beyond: not just a matter of GEFs." in: The EMBO journal, Vol. 19, Issue 11, pp. 2393-8, (2000) (PubMed).
: "Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor." in: Cell, Vol. 73, Issue 3, pp. 611-20, (1993) (PubMed).
Synonyme und alternative Namen zu SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1 (SOS1), son of sevenless homolog 1 (Drosophila) (Sos1), SOS Ras/Rac guanine nucleotide exchange factor 1 (Sos1), 4430401P03Rik, 9630010N06, AI449023, GF1, GGF1, GINGF, HGF, NS4Bezeichner auf Proteinebene für SOS1
- SOS-1
- gingival fibromatosis, hereditary, 1
- guanine nucleotide exchange factor
- son of sevenless homolog 1
- guanine nucleotide releasing factor
- ras guanine exchange factor
- son-of-sevenless 1
- Son of sevenless homolog 1
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