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SOX4 Produkte

(SRY (Sex Determining Region Y)-Box 4 (SOX4))

Kategorien

This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein. [provided by RefSeq, Jul 2008].

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Ausgewählte SOX4 Kategorien

SOX4 Antikörper

High quality antibodies with extensive validation data.

SOX4 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene SOX4 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro)
Validierungen
  • (5)
Kat. Nr. ABIN1387237
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC (p), IF, FACS
Validierungen
  • (1)
  • (4)
Kat. Nr. ABIN388786
Menge 400 μL
Datenblatt Datenblatt

Applikation WB, IHC
Validierungen
  • (13)
Kat. Nr. ABIN2780469
Menge 100 μL
Datenblatt Datenblatt

Empfohlene SOX4 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1321002
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN2732454
Menge 20 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren SOX4 Produkten

Liu, Wu, Zhou, Cai, Li, Hu, Gao, Feng, Wang, Peng, Qi, Liu, Han: "The SOX4/miR-17-92/RB1 Axis Promotes Prostate Cancer Progression." in: Neoplasia (New York, N.Y.), Vol. 21, Issue 8, pp. 765-776, (2019) (PubMed).

Zhou, Wang, Huang, Chen, Zhao, Yao, Jin, Huang, Liu, Li: "Down-regulated SOX4 expression suppresses cell proliferation, metastasis and induces apoptosis in Xuanwei female lung cancer patients." in: Journal of cellular biochemistry, Vol. 116, Issue 6, pp. 1007-18, (2015) (PubMed).

Koumangoye, Andl, Taubenslag, Zilberman, Taylor, Loomans, Andl: "SOX4 interacts with EZH2 and HDAC3 to suppress microRNA-31 in invasive esophageal cancer cells." in: Molecular cancer, Vol. 14, pp. 24, (2015) (PubMed).

Kato, Bhattaram, Penzo-Méndez, Gadi, Lefebvre: "SOXC Transcription Factors Induce Cartilage Growth Plate Formation in Mouse Embryos by Promoting Noncanonical WNT Signaling." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 30, Issue 9, pp. 1560-71, (2015) (PubMed).

Chen, Ruan, Wang, Han, Wang, Lou, Ruan, Qiu, Yang, Zhang: "miR-129-3p, as a diagnostic and prognostic biomarker for renal cell carcinoma, attenuates cell migration and invasion via downregulating multiple metastasis-related genes." in: Journal of cancer research and clinical oncology, Vol. 140, Issue 8, pp. 1295-304, (2014) (PubMed).

Grau, Luque-Garcia, González-Peramato, Theodorescu, Palou, Fernandez-Gomez, Sánchez-Carbayo: "A quantitative proteomic analysis uncovers the relevance of CUL3 in bladder cancer aggressiveness." in: PLoS ONE, Vol. 8, Issue 1, pp. e53328, (2013) (PubMed).

Usui, Mochizuki, Iida, Miyauchi, Satoh, Sock, Nakauchi, Aburatani, Murakami, Wegner, Watanabe: "The early retinal progenitor-expressed gene Sox11 regulates the timing of the differentiation of retinal cells." in: Development (Cambridge, England), Vol. 140, Issue 4, pp. 740-50, (2013) (PubMed).

Medina, Castillo, Blanco, Sanz-Garcia, Largo, Alvarez, Yokota, Gonzalez-Neira, Benitez, Clevers, Cigudosa, Lazo, Sanchez-Cespedes: "The SRY-HMG box gene, SOX4, is a target of gene amplification at chromosome 6p in lung cancer." in: Human molecular genetics, Vol. 18, Issue 7, pp. 1343-52, (2009) (PubMed).

Ruebel, Leontovich, Tanizaki, Jin, Stilling, Zhang, Coonse, Scheithauer, Lombardero, Kovacs, Lloyd: "Effects of TGFbeta1 on gene expression in the HP75 human pituitary tumor cell line identified by gene expression profiling." in: Endocrine, Vol. 33, Issue 1, pp. 62-76, (2008) (PubMed).

Synonyme und alternative Namen zu SOX4

SRY-box 4 (SOX4), SRY box 4 (Sox4), SRY (sex determining region Y)-box 4 (Sox4), SRY (sex determining region Y)-box 4a (sox4a), AA682046, EVI16, Sox-4, sox4, wu:fb82f08, wu:fq41g10, zgc:65850, zgc:77392

Bezeichner auf Proteinebene für SOX4

  • SRY-box containing protein 4
  • transcription factor SOX-4
  • SRY-related HMG-box gene 4
  • ecotropic viral integration site 16
  • SRY-box containing gene 4
  • SRY (sex determining region Y)-box 4
  • SRY (sex determining region Y)-box 4a
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