SPEN Produkte
(Spen Homolog, Transcriptional Regulator (SPEN))
Kategorien
This gene encodes a hormone inducible transcriptional repressor. Repression of transcription by this gene product can occur through interactions with other repressors, by the recruitment of proteins involved in histone deacetylation, or through sequestration of transcriptional activators. The product of this gene contains a carboxy-terminal domain that permits binding to other corepressor proteins. This domain also permits interaction with members of the NuRD complex, a nucleosome remodeling protein complex that contains deacetylase activity. In addition, this repressor contains several RNA recognition motifs that confer binding to a steroid receptor RNA coactivator\; this binding can modulate the activity of both liganded and nonliganded steroid receptors. [provided by RefSeq, Jul 2008].
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Ausgewählte SPEN Kategorien
SPEN Antikörper
High quality antibodies with extensive validation data.
Empfohlene SPEN Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse
Applikation
ELISA
Validierungen
Kat. Nr.
ABIN7096817
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
IP
Validierungen
Kat. Nr.
ABIN7451040
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA
Validierungen
Kat. Nr.
ABIN185595
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren SPEN Produkten
: "SPEN protein expression and interactions with chromatin in mouse testicular cells." in: Reproduction (Cambridge, England), Vol. 156, Issue 3, pp. 195-206, (2018) (PubMed).: "The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3." in: Nature, Vol. 521, Issue 7551, pp. 232-6, (2015) (PubMed).
: "Interaction of the Epstein-Barr virus mRNA export factor EB2 with human Spen proteins SHARP, OTT1, and a novel member of the family, OTT3, links Spen proteins with splicing regulation and mRNA export." in: The Journal of biological chemistry, Vol. 280, Issue 44, pp. 36935-45, (2005) (PubMed).
Synonyme und alternative Namen zu SPEN
spen family transcriptional repressor (SPEN), SPEN homolog, transcriptional regulator (Drosophila) (Spen), HIAA0929, MINT, Mint, mKIAA0929, RBM15C, SHARPBezeichner auf Proteinebene für SPEN
- Msx2 interacting nuclear target (MINT) homolog
- SMART/HDAC1 associated repressor protein
- SMART/HDAC1-associated repressor protein
- msx2-interacting protein
- nuclear receptor transcription cofactor
- spen homolog, transcriptional regulator (Drosophila)
- Msx2 interacting nuclear target protein
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