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SPHK1 Produkte

(Sphingosine Kinase 1 (SPHK1))

Kategorien

The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].

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Ausgewählte SPHK1 Kategorien

SPHK1 Antikörper

High quality antibodies with extensive validation data.

SPHK1 ELISA Kits

Reliable ELISA kits for a wide range of species.

SPHK1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene SPHK1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, IHC (p)
Validierungen
  • (22)
  • (5)
Kat. Nr. ABIN391346
Menge 200 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA
Validierungen
  • (11)
  • (5)
Kat. Nr. ABIN522355
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB
Validierungen
  • (2)
  • (4)
Kat. Nr. ABIN391345
Menge 400 μL
Datenblatt Datenblatt

Empfohlene SPHK1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6959677
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN5510666
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN4884635
Menge 96 tests
Datenblatt Datenblatt

Empfohlene SPHK1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1321162
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1321160
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Baculovirus infected Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN7317043
Menge 50 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren SPHK1 Produkten

Furuya, Shimizu, Tamashiro, Iino, Bielawski, Chan, Pagano, Kawamori: "Sphingosine kinase 1 expression enhances colon tumor growth." in: Journal of translational medicine, Vol. 15, Issue 1, pp. 120, (2018) (PubMed).

Song, Zhang, Chen, Xia, Qin, Waeber, Sheng: "Sphingosine kinase 2 activates autophagy and protects neurons against ischemic injury through interaction with Bcl-2 via its putative BH3 domain." in: Cell death & disease, Vol. 8, Issue 7, pp. e2912, (2018) (PubMed).

Tran, Jersmann, Truong, Hamon, Roscioli, Ween, Pitman, Pitson, Hodge, Reynolds, Hodge: "Disrupted epithelial/macrophage crosstalk via Spinster homologue 2-mediated S1P signaling may drive defective macrophage phagocytic function in COPD." in: PLoS ONE, Vol. 12, Issue 11, pp. e0179577, (2017) (PubMed).

Zhu, You, Tan, Li, Qiu, Li, Huang, Zheng, Ren: "Overexpression of sphingosine kinase 1 is predictive of poor prognosis in human breast cancer." in: Oncology letters, Vol. 14, Issue 1, pp. 63-72, (2017) (PubMed).

Do, Kim, Kim, Lee, Do, Kim, Chae, Sohn: "Predictive Value of Sphingosine Kinase 1 Expression in Papillary Thyroid Carcinoma." in: Anticancer research, Vol. 37, Issue 10, pp. 5399-5405, (2017) (PubMed).

Chen, Gong, Li, Xiong, Wang, Huang, Wang, Chen, Chen, Liu, Lan, Huang: "Sphingosine kinase 1 mediates AGEs-induced fibronectin upregulation in diabetic nephropathy." in: Oncotarget, Vol. 8, Issue 45, pp. 78660-78676, (2017) (PubMed).

Tani, Tabuchi, Hara: "Hair Cell Loss Induced by Sphingosine and a Sphingosine Kinase Inhibitor in the Rat Cochlea." in: Neurotoxicity research, Vol. 29, Issue 1, pp. 35-46, (2016) (PubMed).

Tran, Barnawi, Ween, Hamon, Roscioli, Hodge, Reynolds, Pitson, Davies, Haberberger, Hodge: "Cigarette smoke inhibits efferocytosis via deregulation of sphingosine kinase signaling: reversal with exogenous S1P and the S1P analogue FTY720." in: Journal of leukocyte biology, Vol. 100, Issue 1, pp. 195-202, (2016) (PubMed).

Gairhe, Joshi, Bastola, McLendon, Oka, Fagan, McMurtry: "Sphingosine-1-phosphate is involved in the occlusive arteriopathy of pulmonary arterial hypertension." in: Pulmonary circulation, Vol. 6, Issue 3, pp. 369-80, (2016) (PubMed).

Moles, Urbán, Jiménez-Díaz, Viera-Morilla, Angulo-Barturen, Busquets, Fernàndez-Busquets: "Immunoliposome-mediated drug delivery to Plasmodium-infected and non-infected red blood cells as a dual therapeutic/prophylactic antimalarial strategy." in: Journal of controlled release : official journal of the Controlled Release Society, Vol. 210, pp. 217-29, (2016) (PubMed).

Synonyme und alternative Namen zu SPHK1

Sphingosine kinase 1 (Sk1), sphingosine kinase 1 (SPHK1), sphingosine kinase 1 L homeolog (sphk1.L), sphingosine kinase 1 (Sphk1), 1110006G24Rik, CG1747, Dmel\\CG1747, F18E5.160, F18E5_160, SK1, Sk1, sphingosine kinase 1, SPHK, Sphk1, SPHK1, Spk1

Bezeichner auf Proteinebene für SPHK1

  • CG1747-PA
  • CG1747-PB
  • Sk1-PA
  • Sk1-PB
  • sphingosine kinase 1
  • sphingosine kinase I
  • SK 1
  • SPK 1
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