SPHK2 Produkte
(Sphingosine Kinase 2 (SPHK2))
Kategorien
This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011].
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Ausgewählte SPHK2 Kategorien
SPHK2 Antikörper
High quality antibodies with extensive validation data.
SPHK2 ELISA Kits
Reliable ELISA kits for a wide range of species.
SPHK2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene SPHK2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p)
Validierungen
- (2)
- (4)
Kat. Nr.
ABIN391349
Menge
200 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p)
Validierungen
- (8)
- (2)
Kat. Nr.
ABIN391348
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IP
Validierungen
- (3)
Kat. Nr.
ABIN949506
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene SPHK2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN1381512
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN5592624
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Validierungen
Kat. Nr.
ABIN456114
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene SPHK2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1321164
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1321166
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Insect Cells
Validierungen
Kat. Nr.
ABIN5509153
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren SPHK2 Produkten
: "Sphingosine kinase 2 activates autophagy and protects neurons against ischemic injury through interaction with Bcl-2 via its putative BH3 domain." in: Cell death & disease, Vol. 8, Issue 7, pp. e2912, (2018) (PubMed).: "Disrupted epithelial/macrophage crosstalk via Spinster homologue 2-mediated S1P signaling may drive defective macrophage phagocytic function in COPD." in: PLoS ONE, Vol. 12, Issue 11, pp. e0179577, (2017) (PubMed).
: "Hypoxic preconditioning protects cardiomyocytes against hypoxia/reoxygenation-induced cell apoptosis via sphingosine kinase 2 and FAK/AKT pathway." in: Experimental and molecular pathology, Vol. 100, Issue 1, pp. 51-8, (2016) (PubMed).
: "Hair Cell Loss Induced by Sphingosine and a Sphingosine Kinase Inhibitor in the Rat Cochlea." in: Neurotoxicity research, Vol. 29, Issue 1, pp. 35-46, (2016) (PubMed).
: "Cigarette smoke inhibits efferocytosis via deregulation of sphingosine kinase signaling: reversal with exogenous S1P and the S1P analogue FTY720." in: Journal of leukocyte biology, Vol. 100, Issue 1, pp. 195-202, (2016) (PubMed).
: "Sphingosine-1-phosphate is involved in the occlusive arteriopathy of pulmonary arterial hypertension." in: Pulmonary circulation, Vol. 6, Issue 3, pp. 369-80, (2016) (PubMed).
: "Down-regulation of Sphk2 suppresses bladder cancer progression." in: Tumour biology, (2015) (PubMed).
: "Intracellular sphingosine kinase 2-derived sphingosine-1-phosphate mediates epidermal growth factor-induced ezrin-radixin-moesin phosphorylation and cancer cell invasion." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 29, Issue 11, pp. 4654-69, (2015) (PubMed).
: "Preconditioning stimuli induce autophagy via sphingosine kinase 2 in mouse cortical neurons." in: The Journal of biological chemistry, Vol. 289, Issue 30, pp. 20845-57, (2014) (PubMed).
: "Inducible IL-33 expression by mast cells is regulated by a calcium-dependent pathway." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 189, Issue 7, pp. 3421-9, (2012) (PubMed).
Synonyme und alternative Namen zu SPHK2
Sphingosine kinase (sphK2), sphk2 (sphK2), Sphingosine kinase 2 (Sk2), sphingosine kinase 2 (SPHK2), sphingosine kinase 2 (Sphk2), C76851, CG2159, CG32484, DKFZp469F224, Dmel\\CG32484, SK-2, SK2, sk2, SK 2, Sphk2, SPK-2, SPK 2Bezeichner auf Proteinebene für SPHK2
- Sphingosine kinase
- sphk2
- sphingosine kinase 2
- CG32484-PA
- Sk2-PA
- sphingosine kinase
- sphingosine kinase II
- sphingosine kinase 2-like
- sphingosine kinase type 2
- SK 2
- SPK 2
- Spk2, Sk2
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