SPRY2 Produkte
(Sprouty Homolog 2 (SPRY2))
Kategorien
This gene encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein. [provided by RefSeq, Jul 2008].
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Ausgewählte SPRY2 Kategorien
SPRY2 Antikörper
High quality antibodies with extensive validation data.
SPRY2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene SPRY2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF, IHC (p)
Validierungen
- (3)
- (6)
Kat. Nr.
ABIN564439
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, IF
Validierungen
- (3)
Kat. Nr.
ABIN7170654
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC
Validierungen
- (3)
Kat. Nr.
ABIN7270554
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene SPRY2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6232462
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene SPRY2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1321263
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7405816
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7405819
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren SPRY2 Produkten
: "Induction of Resistance to BRAF Inhibitor Is Associated with the Inability of Spry2 to Inhibit BRAF-V600E Activity in BRAF Mutant Cells." in: Biomolecules & therapeutics, Vol. 23, Issue 4, pp. 320-6, (2015) (PubMed).: "Sprouty2 suppresses the inflammatory responses in rheumatoid arthritis fibroblast-like synoviocytes through regulating the Raf/ERK and PTEN/AKT signals." in: Molecular immunology, Vol. 67, Issue 2 Pt B, pp. 532-9, (2015) (PubMed).
: "SPROUTY2 is a ?-catenin and FOXO3a target gene indicative of poor prognosis in colon cancer." in: Oncogene, Vol. 33, Issue 15, pp. 1975-85, (2014) (PubMed).
: "Initial report on differential expression of sprouty proteins 1 and 2 in human epithelial ovarian cancer cell lines." in: Journal of oncology, Vol. 2012, pp. 373826, (2012) (PubMed).
: "SPROUTY-2 and E-cadherin regulate reciprocally and dictate colon cancer cell tumourigenicity." in: Oncogene, Vol. 29, Issue 34, pp. 4800-13, (2010) (PubMed).
: "Clostridium perfringens Keratitis Leading to Blinding Panophthalmitis." in: Cornea, Vol. 27, Issue 10, pp. 1200-3, (2008) (PubMed).
: "Regulation of vascular smooth muscle cell proliferation and migration by human sprouty 2." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 25, Issue 3, pp. 533-8, (2005) (PubMed).
: "Cerebrovascular and carotid artery disease." in: Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, Vol. 92, Issue 3, pp. 253-6, (2001) (PubMed).
Synonyme und alternative Namen zu SPRY2
sprouty RTK signaling antagonist 2 (spry2), sprouty RTK signaling antagonist 2 (SPRY2), sprouty RTK signaling antagonist 2 S homeolog (spry2.S), sprouty homolog 2 (Drosophila) (Spry2), sprouty RTK signaling antagonist 2 (Spry2), hspry2, hSPRY2, sprouty-2, sprouty2, wu:fk66h11, wu:fk93e11, Xsprouty2, xspry2, Xtsprouty2, zgc:110440Bezeichner auf Proteinebene für SPRY2
- protein sprouty homolog 2
- sprouty 2
- spry-2
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