SPTLC1 Produkte
(serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))
Kategorien
Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate as a cofactor. The product of this gene is the long chain base subunit 1 of serine palmitoyltransferase. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
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Ausgewählte SPTLC1 Kategorien
SPTLC1 Antikörper
High quality antibodies with extensive validation data.
SPTLC1 ELISA Kits
Reliable ELISA kits for a wide range of species.
SPTLC1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene SPTLC1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC (p)
Validierungen
- (6)
Kat. Nr.
ABIN3187765
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Mouse
Applikation
WB, IHC, IP, ICC
Validierungen
- (4)
Kat. Nr.
ABIN7436414
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC
Validierungen
- (3)
Kat. Nr.
ABIN7168895
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene SPTLC1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6970110
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6959376
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN5658719
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene SPTLC1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1321282
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7399220
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3131665
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren SPTLC1 Produkten
: "Transcriptional Differences in Lipid-Metabolizing Enzymes in Murine Sebocytes Derived from Sebaceous Glands of the Skin and Preputial Glands." in: International journal of molecular sciences, Vol. 22, Issue 21, (2021) (PubMed).: "Expression of the ORMDLS, modulators of serine palmitoyltransferase, is regulated by sphingolipids in mammalian cells." in: The Journal of biological chemistry, Vol. 290, Issue 1, pp. 90-8, (2015) (PubMed).
: "Serine palmitoyltransferase subunit 1 is present in the endoplasmic reticulum, nucleus and focal adhesions, and functions in cell morphology." in: Biochimica et biophysica acta, Vol. 1791, Issue 8, pp. 746-56, (2009) (PubMed).
: "Apoptotic sphingolipid signaling by ceramides in lung endothelial cells." in: American journal of respiratory cell and molecular biology, Vol. 38, Issue 6, pp. 639-46, (2008) (PubMed).
: "Permeability barrier disruption increases the level of serine palmitoyltransferase in human epidermis." in: The Journal of investigative dermatology, Vol. 119, Issue 5, pp. 1048-52, (2002) (PubMed).
: "Mutations in SPTLC1, encoding serine palmitoyltransferase, long chain base subunit-1, cause hereditary sensory neuropathy type I." in: Nature genetics, Vol. 27, Issue 3, pp. 309-12, (2001) (PubMed).
: "Minocycline inhibits microglial activation and protects nigral cells after 6-hydroxydopamine injection into mouse striatum." in: Brain research, Vol. 909, Issue 1-2, pp. 187-93, (2001) (PubMed).
: "A mammalian homolog of the yeast LCB1 encodes a component of serine palmitoyltransferase, the enzyme catalyzing the first step in sphingolipid synthesis." in: The Journal of biological chemistry, Vol. 272, Issue 51, pp. 32108-14, (1998) (PubMed).
: "Human and murine serine-palmitoyl-CoA transferase--cloning, expression and characterization of the key enzyme in sphingolipid synthesis." in: European journal of biochemistry / FEBS, Vol. 249, Issue 1, pp. 239-47, (1997) (PubMed).
Synonyme und alternative Namen zu SPTLC1
serine palmitoyltransferase 1 (SPT1), serine palmitoyltransferase 1 (AFUA_6G00300), Serine palmitoyltransferase 1 (PAS_FragB_0040), serine palmitoyltransferase long chain base subunit 1 (SPTLC1), serine palmitoyltransferase, long chain base subunit 1 (sptlc1), serine palmitoyltransferase, long chain base subunit 1 L homeolog (sptlc1.L), serine palmitoyltransferase, long chain base subunit 1 (Sptlc1), serine palmitoyltransferase long chain base subunit 1 (Sptlc1), Afu6g00300, ATSPT1, AW552086, C77762, E030036H05, HSAN1, HSN1, LBC1, LCB1, Lcb1, RGD1306617, SERINE PALMITOYLTRANSFERASE 1, serine palmitoyltransferase 1, SPT1, Spt1, SPTI, wu:fc75h04, wu:fp41c08, zgc:112247Bezeichner auf Proteinebene für SPTLC1
- Serine palmitoyltransferase 1
- LCB 1
- SPT 1
- long chain base biosynthesis protein 1
- serine C-palmitoyltransferase
- serine palmitoyltransferase 1
- serine-palmitoyl-CoA transferase 1
- fc75h04
- fp41c08
- SPT1
- serine palmitoyltransferase subunit 1
- Long chain base biosynthesis protein 1
- Serine-palmitoyl-CoA transferase 1
- serine palmitoyltransferase LCB1 subunit
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