ST14 Produkte
(Suppression of Tumorigenicity 14 (Colon Carcinoma) (ST14))
Kategorien
The protein encoded by this gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis. [provided by RefSeq, Jul 2008].
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Ausgewählte ST14 Kategorien
ST14 Antikörper
High quality antibodies with extensive validation data.
ST14 ELISA Kits
Reliable ELISA kits for a wide range of species.
ST14 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene ST14 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validierungen
- (4)
Kat. Nr.
ABIN669726
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, IHC (p)
Validierungen
- (3)
Kat. Nr.
ABIN652185
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, ELISA, IHC, IF, ICC
Validierungen
- (3)
Kat. Nr.
ABIN6263143
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene ST14 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6959763
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN4883709
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6386252
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene ST14 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1321472
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1321474
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7505189
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren ST14 Produkten
: "Developmental mechanisms driving complex tooth shape in reptiles." in: Developmental dynamics : an official publication of the American Association of Anatomists, Vol. 249, Issue 4, pp. 441-464, (2020) (PubMed).: "Conserved function of the matriptase-prostasin proteolytic cascade during epithelial morphogenesis." in: PLoS genetics, Vol. 15, Issue 1, pp. e1007882, (2019) (PubMed).
: "Inflammatory cytokines down-regulate the barrier-protective prostasin-matriptase proteolytic cascade early in experimental colitis." in: The Journal of biological chemistry, Vol. 292, Issue 26, pp. 10801-10812, (2017) (PubMed).
: "Matriptase zymogen supports epithelial development, homeostasis and regeneration." in: BMC biology, Vol. 15, Issue 1, pp. 46, (2017) (PubMed).
: "Distinct Developmental Functions of Prostasin (CAP1/PRSS8) Zymogen and Activated Prostasin." in: The Journal of biological chemistry, Vol. 291, Issue 6, pp. 2577-82, (2016) (PubMed).
: "Targeting matriptase in breast cancer abrogates tumour progression via impairment of stromal-epithelial growth factor signalling." in: Nature communications, Vol. 6, pp. 6776, (2015) (PubMed).
: "Matriptase promotes inflammatory cell accumulation and progression of established epidermal tumors." in: Oncogene, Vol. 34, Issue 35, pp. 4664-72, (2015) (PubMed).
: "Epigenetic Silencing of SPINT2 Promotes Cancer Cell Motility via HGF-MET Pathway Activation in Melanoma." in: The Journal of investigative dermatology, Vol. 135, Issue 9, pp. 2283-91, (2015) (PubMed).
: "Regulation of feto-maternal barrier by matriptase- and PAR-2-mediated signaling is required for placental morphogenesis and mouse embryonic survival." in: PLoS genetics, Vol. 10, Issue 7, pp. e1004470, (2015) (PubMed).
: "Matriptase proteolytically activates influenza virus and promotes multicycle replication in the human airway epithelium." in: Journal of virology, Vol. 87, Issue 8, pp. 4237-51, (2013) (PubMed).
Synonyme und alternative Namen zu ST14
suppression of tumorigenicity 14 (ST14), suppression of tumorigenicity 14 L homeolog (st14.L), suppression of tumorigenicity 14 (colon carcinoma) (St14), suppression of tumorigenicity 14 (St14), Epithin, HAI, hai, matriptase, mCAP3, MT-SP1, mt-sp1, MTSP1, mtsp1, PRSS14, prss14, Prss14, SNC19, snc19, st14, st14a, TADG15, tadg15, tmprss1, TMPRSS14, Tmprss14, XMT-SP1Bezeichner auf Proteinebene für ST14
- membrane-type serine protease 1
- prostamin
- serine protease 14
- serine protease TADG-15
- suppression of tumorigenicity 14 (colon carcinoma, matriptase, epithin)
- suppressor of tumorigenicity 14 protein
- tumor associated differentially expressed gene 15 protein
- tumor-associated differentially-expressed gene 15 protein
- matriptase a
- suppression of tumorigenicity 14 (colon carcinoma) a
- suppressor of tumorigenicity 14 protein homolog
- suppressor of tumorigenicity protein 14
- matriptase/MT-SP1
- protease, serine, 14 (epithin)
- matriptase
- membrane-type serine protease
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