STAT2 Produkte
(Signal Transducer and Activator of Transcription 2, 113kDa (STAT2))
Kategorien
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010].
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Ausgewählte STAT2 Kategorien
STAT2 Antikörper
High quality antibodies with extensive validation data.
STAT2 ELISA Kits
Reliable ELISA kits for a wide range of species.
STAT2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene STAT2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (7)
Kat. Nr.
ABIN7434083
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Rat
Applikation
WB, IHC, IP, ICC
Validierungen
- (7)
Kat. Nr.
ABIN7443368
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validierungen
- (6)
Kat. Nr.
ABIN738246
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene STAT2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validierungen
- (3)
Kat. Nr.
ABIN5691024
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6970214
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6970213
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene STAT2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1321592
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7394858
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7406047
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren STAT2 Produkten
: "STAT1 is essential for the inhibition of hepatitis C virus replication by interferon-λ but not by interferon-α." in: Scientific reports, Vol. 6, pp. 38336, (2018) (PubMed).: "Porcine Deltacoronavirus nsp5 Antagonizes Type I Interferon Signaling by Cleaving STAT2." in: Journal of virology, Vol. 91, Issue 10, (2017) (PubMed).
: "JAK3 as an Emerging Target for Topical Treatment of Inflammatory Skin Diseases." in: PloS one, Vol. 11, Issue 10, pp. e0164080, (2017) (PubMed).
: "The detrimental effects of IFN-α on vasculogenesis in lupus are mediated by repression of IL-1 pathways: potential role in atherogenesis and renal vascular rarefaction." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 185, Issue 7, pp. 4457-69, (2010) (PubMed).
: "Regulation of arsenic trioxide-induced cellular responses by Mnk1 and Mnk2." in: The Journal of biological chemistry, Vol. 283, Issue 18, pp. 12034-42, (2008) (PubMed).
: "Suppression of interferon (IFN)-inducible genes and IFN-mediated functional responses in BCR-ABL-expressing cells." in: The Journal of biological chemistry, Vol. 283, Issue 16, pp. 10793-803, (2008) (PubMed).
: "Upregulation of a small subset of genes drives type I interferon-induced antiviral memory." in: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, Vol. 27, Issue 8, pp. 653-64, (2007) (PubMed).
: "Stats: multifaceted regulators of transcription." in: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, Vol. 25, Issue 12, pp. 733-44, (2005) (PubMed).
: "Functional relevance of the conserved DNA-binding domain of STAT2." in: The Journal of biological chemistry, Vol. 280, Issue 13, pp. 13029-36, (2005) (PubMed).
: "STAT2 nuclear trafficking." in: The Journal of biological chemistry, Vol. 279, Issue 38, pp. 39199-206, (2004) (PubMed).
Synonyme und alternative Namen zu STAT2
signal transducer and activator of transcription 2 (stat2), signal transducer and activator of transcription 2 (STAT2), AGAP000099-PA (STAT2), signal transducer and activator of transcription 2 (Stat2), 1600010G07Rik, AW496480, ISGF-3, p113, P113, stat2, STAT113, wu:fj84d07Bezeichner auf Proteinebene für STAT2
- fj84d07
- signal transducer and activator of transcription 2
- signal transducer and activator of transcription (AGAP000099-PA)
- interferon alpha induced transcriptional activator
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