STAT4 Produkte
(Signal Transducer and Activator of Transcription 4 (STAT4))
Kategorien
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011].
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Ausgewählte STAT4 Kategorien
STAT4 Antikörper
High quality antibodies with extensive validation data.
STAT4 ELISA Kits
Reliable ELISA kits for a wide range of species.
STAT4 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene STAT4 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (6)
Kat. Nr.
ABIN7443809
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC, IF
Validierungen
- (7)
Kat. Nr.
ABIN7262925
Menge
200 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IP, IF, IHC (p)
Validierungen
- (9)
Kat. Nr.
ABIN563030
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene STAT4 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Analytical Method
Semi-Quantitative Cell ELISA
Validierungen
- (3)
- (5)
Kat. Nr.
ABIN1981841
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6970219
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6970218
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene STAT4 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1321598
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7417414
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3134026
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren STAT4 Produkten
: "The effect of the TLR9 ligand CpG-oligodeoxynucleotide on the protective immune response to radiation-induced lung fibrosis in mice." in: Molecular immunology, Vol. 80, pp. 33-40, (2017) (PubMed).: "Radiation-induced lung fibrosis in a tumor-bearing mouse model is associated with enhanced Type-2 immunity." in: Journal of radiation research, Vol. 57, Issue 2, pp. 133-41, (2017) (PubMed).
: "A guanidine-rich regulatory oligodeoxynucleotide improves type-2 diabetes in obese mice by blocking T-cell differentiation." in: EMBO molecular medicine, Vol. 4, Issue 10, pp. 1112-25, (2012) (PubMed).
: "Temporal induction pattern of STAT4 target genes defines potential for Th1 lineage-specific programming." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 6, pp. 3839-47, (2009) (PubMed).
: "High basal STAT4 balanced by STAT1 induction to control type 1 interferon effects in natural killer cells." in: The Journal of experimental medicine, Vol. 204, Issue 10, pp. 2383-96, (2007) (PubMed).
: "Interferon alpha but not interleukin 12 activates STAT4 signaling in human vascular endothelial cells." in: The Journal of biological chemistry, Vol. 279, Issue 25, pp. 26789-96, (2004) (PubMed).
: "PIASx is a transcriptional co-repressor of signal transducer and activator of transcription 4." in: The Journal of biological chemistry, Vol. 278, Issue 24, pp. 21327-30, (2003) (PubMed).
: "Signaling through the JAK/STAT pathway, recent advances and future challenges." in: Gene, Vol. 285, Issue 1-2, pp. 1-24, (2002) (PubMed).
: "Activated STAT4 and a functional role for IL-12 in human Peyer's patches." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 1, pp. 300-7, (2002) (PubMed).
: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, (2002) (PubMed).
Synonyme und alternative Namen zu STAT4
signal transducer and activator of transcription 4 (STAT4), signal transducer and activator of transcription 4 (stat4), signal transducer and activator of transcription 4 (Stat4), SLEB11Bezeichner auf Proteinebene für STAT4
- signal transducer and activator of transcription 4
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