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STAT5B Produkte

(Signal Transducer and Activator of Transcription 5B (STAT5B))

Kategorien

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. [provided by RefSeq, Jul 2008].

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Ausgewählte STAT5B Kategorien

STAT5B Antikörper

High quality antibodies with extensive validation data.

STAT5B ELISA Kits

Reliable ELISA kits for a wide range of species.

STAT5B Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene STAT5B Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF
Validierungen
  • (5)
Kat. Nr. ABIN563035
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IP
Validierungen
  • (5)
Kat. Nr. ABIN520547
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF, IHC (p)
Validierungen
  • (5)
Kat. Nr. ABIN520546
Menge 100 μg
Datenblatt Datenblatt

Empfohlene STAT5B ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6959478
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6970221
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN1117115
Menge 96 tests
Datenblatt Datenblatt

Empfohlene STAT5B Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7125095
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1321604
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1321606
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren STAT5B Produkten

Lin, Du, Li, Kazemian, Gebregiorgis, Spolski, Leonard: "Critical functions for STAT5 tetramers in the maturation and survival of natural killer cells." in: Nature communications, Vol. 8, Issue 1, pp. 1320, (2018) (PubMed).

Kobayashi, Watanabe, Suzuki, Furu, Ito, Ito, Matsuda, Yoshitomi: "TGF-β induces the differentiation of human CXCL13-producing CD4(+) T cells." in: European journal of immunology, Vol. 46, Issue 2, pp. 360-71, (2016) (PubMed).

Schaller-Schönitz, Barzan, Williamson, Griffiths, Dallmann, Battmer, Ganser, Whetton, Scherr, Eder: "BCR-ABL affects STAT5A and STAT5B differentially." in: PLoS ONE, Vol. 9, Issue 5, pp. e97243, (2015) (PubMed).

Zheng, Xiong, Wu, Chen, Chen, Fleming, Gao, Bi, Ge: "Quantitative Proteomics Analysis Reveals Novel Insights into Mechanisms of Action of Long Noncoding RNA Hox Transcript Antisense Intergenic RNA (HOTAIR) in HeLa Cells." in: Molecular & cellular proteomics : MCP, Vol. 14, Issue 6, pp. 1447-63, (2015) (PubMed).

Uchino, Iriyama, Hatta, Takei: "Granulocyte colony-stimulating factor potentiates all-trans retinoic acid-induced granulocytic differentiation in acute promyelocytic leukemia cell line HT93A." in: Cancer cell international, Vol. 15, pp. 30, (2015) (PubMed).

Sun, Wang, Yan, Lu, Shi: "Effects of Er-Zhi-Wan on microarchitecture and regulation of Wnt/?-catenin signaling pathway in alveolar bone of ovariectomized rats." in: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, Vol. 34, Issue 1, pp. 114-9, (2014) (PubMed).

Pastuszak-Lewandoska, Doma?ska, Czarnecka, Kordiak, Migdalska-S?k, Nawrot, Kisza?kiewicz, Antczak, Górski, Brzezia?ska: "Expression of STAT5, COX-2 and PIAS3 in correlation with NSCLC histhopathological features." in: PLoS ONE, Vol. 9, Issue 8, pp. e104265, (2014) (PubMed).

Rajala, Eldfors, Kuusanmäki, van Adrichem, Olson, Lagström, Andersson, Jerez, Clemente, Yan, Zhang, Awwad, Ellonen, Kallioniemi, Wennerberg, Porkka, Maciejewski, Loughran, Heckman, Mustjoki: "Discovery of somatic STAT5b mutations in large granular lymphocytic leukemia." in: Blood, Vol. 121, Issue 22, pp. 4541-50, (2013) (PubMed).

Mitra, Ross, Rodriguez, Nagy, Wilson, Kirken: "Signal transducer and activator of transcription 5b (Stat5b) serine 193 is a novel cytokine-induced phospho-regulatory site that is constitutively activated in primary hematopoietic malignancies." in: The Journal of biological chemistry, Vol. 287, Issue 20, pp. 16596-608, (2012) (PubMed).

Pullen, Barnstein, Falanga, Wang, Suzuki, Lama Tamang, Khurana, Harry, Rivera, Draber, Bunting, Mizuno, Wilson, Ryan: "A novel mechanism for Fc{epsilon}RI-mediated signal transducer and activator of transcription 5 (Stat5) tyrosine phosphorylation and the selective influence of Stat5B over mast cell cytokine production." in: The Journal of biological chemistry, (2011) (PubMed).

Synonyme und alternative Namen zu STAT5B

signal transducer and activator of transcription 5B (STAT5B), signal transducer and activator of transcription 5B (Stat5b), signal transducer and activator of transcription 5B S homeolog (stat5b.S), signal transducer and activator of transcription 5B (LOC490969), Signal transducer and activator of transcription 5B (sta5b), signal transducer and activator of transcription 5B (LOC100566752), signal transducer and activator of transcription 5B (LOC100052954), STAT5, stat5, STAT5A, STAT5B

Bezeichner auf Proteinebene für STAT5B

  • transcription factor STAT5B
  • Signal transducer and activator of transcription 5a
  • mammary gland factor STAT5B
  • signal transducer and activator of transcription 5A
  • Signal transducer and activator of transcription 5B
  • signal transducer and activator of transcription 5B
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