STAT6 Produkte
(Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6))
Kategorien
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010].
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Ausgewählte STAT6 Kategorien
STAT6 Antikörper
High quality antibodies with extensive validation data.
STAT6 ELISA Kits
Reliable ELISA kits for a wide range of species.
STAT6 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene STAT6 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC (p), IF
Validierungen
- (6)
Kat. Nr.
ABIN563038
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC, ELISA, IP, ICC, IF
Validierungen
- (5)
Kat. Nr.
ABIN6255720
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF
Validierungen
- (5)
Kat. Nr.
ABIN6148581
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene STAT6 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Analytical Method
Semi-Quantitative Cell ELISA
Validierungen
- (1)
- (5)
Kat. Nr.
ABIN1981845
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validierungen
- (3)
Kat. Nr.
ABIN1981731
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validierungen
- (3)
Kat. Nr.
ABIN4889794
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene STAT6 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7125097
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7125096
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1321610
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren STAT6 Produkten
: "Absence of Tumor Necrosis Factor Supports Alternative Activation of Macrophages in the Liver after Infection with Leishmania major." in: Frontiers in immunology, Vol. 9, pp. 1, (2019) (PubMed).: "Hydrogen sulfide attenuates myocardial fibrosis in diabetic rats through the JAK/STAT signaling pathway." in: International journal of molecular medicine, Vol. 41, Issue 4, pp. 1867-1876, (2018) (PubMed).
: "Inhibition of CRTH2-mediated Th2 activation attenuates pulmonary hypertension in mice." in: The Journal of experimental medicine, Vol. 215, Issue 8, pp. 2175-2195, (2018) (PubMed).
: "Niacin Promotes Cardiac Healing after Myocardial Infarction through Activation of the Myeloid Prostaglandin D2 Receptor Subtype 1." in: The Journal of pharmacology and experimental therapeutics, Vol. 360, Issue 3, pp. 435-444, (2017) (PubMed).
: "Oral exposure to diisodecyl phthalate aggravates allergic dermatitis by oxidative stress and enhancement of thymic stromal lymphopoietin." in: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Vol. 99, pp. 60-69, (2017) (PubMed).
: "The effect of the TLR9 ligand CpG-oligodeoxynucleotide on the protective immune response to radiation-induced lung fibrosis in mice." in: Molecular immunology, Vol. 80, pp. 33-40, (2017) (PubMed).
: "Radiation-induced lung fibrosis in a tumor-bearing mouse model is associated with enhanced Type-2 immunity." in: Journal of radiation research, Vol. 57, Issue 2, pp. 133-41, (2017) (PubMed).
: "IL-4 Downregulates IL-1β and IL-6 and Induces GATA3 in Psoriatic Epidermal Cells: Route of Action of a Th2 Cytokine." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 4, pp. 1744-52, (2015) (PubMed).
: "STATs profiling reveals predominantly-activated STAT3 in cholangiocarcinoma genesis and progression." in: Journal of hepato-biliary-pancreatic sciences, Vol. 21, Issue 10, pp. 767-76, (2014) (PubMed).
: "The role of STAT-6 as a key transcription regulator in HeLa cell death induced by IFN-?/TNF-? co-immobilized on nanoparticles." in: Biomaterials, Vol. 35, Issue 18, pp. 5016-27, (2014) (PubMed).
Synonyme und alternative Namen zu STAT6
signal transducer and activator of transcription 6 (STAT6), signal transducer and activator of transcription 6 (Stat6), signal transducer and activator of transcription 6-like (LOC100859543), D12S1644, IL-4-STAT, STAT6B, STAT6CBezeichner auf Proteinebene für STAT6
- signal transducer and transcription activator 6
- STAT, interleukin4-induced
- signal transducer and activator of transcription 6
- transcription factor IL-4 STAT
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- Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2)
- Sterol Carrier Protein 2
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