Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) Produkte
(Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) (SRD5A2))
Kategorien
This gene encodes a microsomal protein expressed at high levels in androgen-sensitive tissues such as the prostate. The encoded protein is active at acidic pH and is sensitive to the 4-azasteroid inhibitor finasteride. Deficiencies in this gene can result in male pseudohermaphroditism, specifically pseudovaginal perineoscrotal hypospadias (PPSH). [provided by RefSeq, Jul 2008].
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Ausgewählte Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) Kategorien
Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) Antikörper
High quality antibodies with extensive validation data.
Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) ELISA Kits
Reliable ELISA kits for a wide range of species.
Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (1)
- (2)
Kat. Nr.
ABIN520465
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF
Validierungen
- (3)
Kat. Nr.
ABIN7270595
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Pig, Rabbit
Applikation
WB, IHC
Validierungen
- (1)
- (3)
Kat. Nr.
ABIN2781788
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (2)
- (1)
Kat. Nr.
ABIN6959725
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6962626
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6959723
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1321302
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Rat
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7409836
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7409833
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) Produkten
: "TSPO activation modulates the effects of high pressure in a rat ex vivo glaucoma model." in: Neuropharmacology, Vol. 111, pp. 142-159, (2016) (PubMed).: "The role of 5α-reductase type 1 associated with intratumoral dihydrotestosterone concentrations in human endometrial carcinoma." in: Molecular and cellular endocrinology, Vol. 401, pp. 56-64, (2015) (PubMed).
: "Hamster SRD5A3 lacks steroid 5α-reductase activity in vitro." in: Steroids, Vol. 94, pp. 41-50, (2015) (PubMed).
: "Localization of the androgen-synthesizing enzymes, androgen receptor, and sex steroids in the vagina: possible implications for the treatment of postmenopausal sexual dysfunction." in: The journal of sexual medicine, Vol. 11, Issue 8, pp. 1949-61, (2014) (PubMed).
: "Resistance training restores muscle sex steroid hormone steroidogenesis in older men." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 28, Issue 4, pp. 1891-7, (2014) (PubMed).
: "Seoritae extract reduces prostate weight and suppresses prostate cell proliferation in a rat model of benign prostate hyperplasia." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2014, pp. 475876, (2014) (PubMed).
: "46,XY disorder of sexual development resulting from a novel monoallelic mutation (p.Ser31Phe) in the steroid 5α-reductase type-2 (SRD5A2) gene." in: Molecular genetics & genomic medicine, Vol. 2, Issue 4, pp. 292-6, (2014) (PubMed).
: "DHEA administration activates local bioactive androgen metabolism in cancellous site of tibia of ovariectomized rats." in: Calcified tissue international, Vol. 89, Issue 2, pp. 105-10, (2011) (PubMed).
: "Molecular analysis of the SRD5A2 in 46,XY subjects with incomplete virilization: the P212R substitution of the steroid 5alpha-reductase 2 may constitute an ancestral founder mutation in Mexican ..." in: Journal of andrology, Vol. 31, Issue 4, pp. 358-64, (2010) (PubMed).
: "VDR and SRD5A2 polymorphisms combine to increase risk for prostate cancer in both non-Hispanic White and Hispanic White men." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 14, Issue 10, pp. 3223-9, (2008) (PubMed).
Synonyme und alternative Namen zu Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2)
steroid 5 alpha-reductase 2 (SRD5A2), steroid 5 alpha-reductase 2 (Srd5a2), steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) (srd5a2), 3-oxo-5-alpha-steroid 4-dehydrogenase 2 (LOC100125532), steroid-5-alpha-reductase, alpha polypeptide 2a (srd5a2a), steroid-5-alpha-reductase, alpha polypeptide 2b (srd5a2b), 5ART2, CH73-233A22.6, S5AR 2, SRD5A2, Srd5a2, SRD5alpha2, wu:fk70d02, zgc:109942, zgc:112208, zgc:112455Bezeichner auf Proteinebene für Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2)
- 3-oxo-5-alpha-steroid 4-dehydrogenase 2
- 5 alpha-SR2
- S5AR 2
- SR type 2
- steroid 5-alpha-reductase 2
- type II 5-alpha reductase
- steroid 5 alpha reductase type2
- prostatic steroid 5-alpha-reductase type II
- steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
- steroid-5-alpha-reductase alpha polypeptide 2
- steroid-5-alpha-reductase, alpha polypeptide 2b
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