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STIM1 Produkte

(Stromal Interaction Molecule 1 (STIM1))

Kategorien

This gene encodes a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs). It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region, as well as early hematopoiesis, by mediating attachment to stromal cells. This gene is oriented in a head-to-tail configuration with the ribonucleotide reductase 1 gene (RRM1), with the 3' end of this gene situated 1.6 kb from the 5' end of the RRM1 gene.[provided by RefSeq, Jan 2009].

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Ausgewählte STIM1 Kategorien

STIM1 Antikörper

High quality antibodies with extensive validation data.

STIM1 ELISA Kits

Reliable ELISA kits for a wide range of species.

STIM1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene STIM1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC (p), IF
Validierungen
  • (20)
  • (5)
Kat. Nr. ABIN563045
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (5)
Kat. Nr. ABIN7444409
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, IP, IHC (p), ICC
Validierungen
  • (2)
  • (3)
Kat. Nr. ABIN192394
Menge 0.1 mg
Datenblatt Datenblatt

Empfohlene STIM1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6730286
Menge 96 tests
Datenblatt Datenblatt

Empfohlene STIM1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN1321631
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN666653
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7418308
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren STIM1 Produkten

Zhou, Gu, Li, Li, Zhu, Gao, Zang, Wang, Shan, Yang: "Suppression of STIM1 inhibits the migration and invasion of human prostate cancer cells and is associated with PI3K/Akt signaling inactivation." in: Oncology reports, Vol. 38, Issue 5, pp. 2629-2636, (2018) (PubMed).

Wu, Hsu, Wang, Liang, Tsai, Yen, Li, Chiu, Chang, Huang, Lin, Yoshioka: "A Novel Strategy for TNF-Alpha Production by 2-APB Induced Downregulated SOCE and Upregulated HSP70 in O. tsutsugamushi-Infected Human Macrophages." in: PLoS ONE, Vol. 11, Issue 7, pp. e0159299, (2017) (PubMed).

Chen, Zhang, Wu, Shi, Yan, Mei, Tolleson, Guo: "Endoplasmic Reticulum Stress and Store-Operated Calcium Entry Contribute to Usnic Acid-Induced Toxicity in Hepatic Cells." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 146, Issue 1, pp. 116-26, (2015) (PubMed).

Hong, Chang, Wang, Yu, Lee: "IL-9 induces IL-8 production via STIM1 activation and ERK phosphorylation in epidermal keratinocytes: A plausible mechanism of IL-9R in atopic dermatitis." in: Journal of dermatological science, Vol. 78, Issue 3, pp. 206-14, (2015) (PubMed).

Wang, Choi, Richardson, Reid, Seymen, Yildirim, Tuna, Gençay, Simmer, Hu: "STIM1 and SLC24A4 Are Critical for Enamel Maturation." in: Journal of dental research, Vol. 93, Issue 7 Suppl, pp. 94S-100S, (2015) (PubMed).

Shalygin, Skopin, Kalinina, Zimina, Glushankova, Mozhayeva, Kaznacheyeva: "STIM1 and STIM2 proteins differently regulate endogenous store-operated channels in HEK293 cells." in: The Journal of biological chemistry, Vol. 290, Issue 8, pp. 4717-27, (2015) (PubMed).

Sogkas, Stegner, Syed, Vögtle, Rau, Gewecke, Schmidt, Nieswandt, Gessner: "Cooperative and alternate functions for STIM1 and STIM2 in macrophage activation and in the context of inflammation." in: Immunity, inflammation and disease, Vol. 3, Issue 3, pp. 154-70, (2015) (PubMed).

Tirado-Lee, Yamashita, Prakriya: "Conformational Changes in the Orai1 C-Terminus Evoked by STIM1 Binding." in: PLoS ONE, Vol. 10, Issue 6, pp. e0128622, (2015) (PubMed).

Ma, Wei, He, Liu, Wu, Zhang, Jing, Liang, Senes, Tan, Li, Sun, Bi, Zhong, Si, Shen, Li, Lee, Zhou, Wang, Wang, Zhou: "Inside-out Ca(2+) signalling prompted by STIM1 conformational switch." in: Nature communications, Vol. 6, pp. 7826, (2015) (PubMed).

Samanta, Kar, Mirams, Parekh: "Ca(2+) Channel Re-localization to Plasma-Membrane Microdomains Strengthens Activation of Ca(2+)-Dependent Nuclear Gene Expression." in: Cell reports, Vol. 12, Issue 2, pp. 203-16, (2015) (PubMed).

Synonyme und alternative Namen zu STIM1

stromal interaction molecule 1 (STIM1), stromal interaction molecule 1 (stim1), stromal interaction molecule 1a (stim1a), stromal interaction molecule 1 L homeolog (stim1.L), stromal interaction molecule 1b (stim1b), stromal interaction molecule 1 (Stim1), D11S4896E, GOK, MGC76045, MGC154748, si:ch211-112l17.2, si:dkey-24p1.5, SIM, stim1, STIM1, Stim1, TAM

Bezeichner auf Proteinebene für STIM1

  • stromal interaction molecule 1
  • stromal interaction molecule 1b
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