STK4 Produkte
(serine/threonine Kinase 4 (STK4))
Kategorien
The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process. [provided by RefSeq, Jul 2008].
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Ausgewählte STK4 Kategorien
STK4 Antikörper
High quality antibodies with extensive validation data.
STK4 ELISA Kits
Reliable ELISA kits for a wide range of species.
STK4 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene STK4 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF, PLA
Validierungen
- (8)
Kat. Nr.
ABIN563051
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF, IHC (p)
Validierungen
- (5)
Kat. Nr.
ABIN563050
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IP, IF, IHC (p), ICC
Validierungen
- (5)
Kat. Nr.
ABIN2856667
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene STK4 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN1889361
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6231399
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene STK4 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1321708
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1321706
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Baculovirus infected Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN7317074
Menge
50 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren STK4 Produkten
: "Protein kinase A inhibitor, H89, enhances survival and clonogenicity of dissociated human embryonic stem cells through Rho-associated coiled-coil containing protein kinase (ROCK) inhibition." in: Human reproduction (Oxford, England), Vol. 31, Issue 4, pp. 832-43, (2016) (PubMed).: "Identification of MST1/STK4 and SULF1 proteins as autoantibody targets for the diagnosis of colorectal cancer by using phage microarrays." in: Molecular & cellular proteomics : MCP, Vol. 10, Issue 3, pp. M110.001784, (2011) (PubMed).
: "Tumor suppressor ras association domain family 5 (RASSF5/NORE1) mediates death receptor ligand-induced apoptosis." in: The Journal of biological chemistry, Vol. 285, Issue 45, pp. 35029-38, (2010) (PubMed).
: "Down-regulation of mammalian sterile 20-like kinase 1 by heat shock protein 70 mediates cisplatin resistance in prostate cancer cells." in: Cancer research, Vol. 68, Issue 7, pp. 2266-74, (2008) (PubMed).
: "Merlin is a potent inhibitor of glioma growth." in: Cancer research, Vol. 68, Issue 14, pp. 5733-42, (2008) (PubMed).
: "Frequent hypermethylation of MST1 and MST2 in soft tissue sarcoma." in: Molecular carcinogenesis, Vol. 46, Issue 10, pp. 865-71, (2007) (PubMed).
: "Akt phosphorylates MstI and prevents its proteolytic activation, blocking FOXO3 phosphorylation and nuclear translocation." in: The Journal of biological chemistry, Vol. 282, Issue 42, pp. 30836-44, (2007) (PubMed).
: "The pro-apoptotic kinase Mst1 and its caspase cleavage products are direct inhibitors of Akt1." in: The EMBO journal, Vol. 26, Issue 21, pp. 4523-34, (2007) (PubMed).
Synonyme und alternative Namen zu STK4
serine/threonine kinase 4 (STK4), serine/threonine kinase 4 (Stk4), serine/threonine kinase 4 S homeolog (stk4.S), AI447339, AU020804, Kas-2, KRS2, krs2, MST1, Mst1, mst1, TIIAC, YSK3, Ysk3, ysk3Bezeichner auf Proteinebene für STK4
- MST-1
- STE20-like kinase MST1
- dJ211D12.2 (serine/threonine kinase 4 (MST1, KRS2))
- kinase responsive to stress 2
- mammalian STE20-like protein kinase 1
- mammalian sterile 20-like 1
- serine/threonine-protein kinase 4
- serine/threonine-protein kinase Krs-2
- Yeast Sps1/Ste20-related kinase 3
- sterile 20-like kinase 1
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