STRADA Produkte
(STE20-Related Kinase Adaptor alpha (STRADA))
Kategorien
The protein encoded by this gene contains a STE20-like kinase domain, but lacks several residues that are critical for catalytic activity, so it is termed a 'pseudokinase'. The protein forms a heterotrimeric complex with serine/threonine kinase 11 (STK11, also known as LKB1) and the scaffolding protein calcium binding protein 39 (CAB39, also known as MO25). The protein activates STK11 leading to the phosphorylation of both proteins and excluding STK11 from the nucleus. The protein is necessary for STK11-induced G1 cell cycle arrest. A mutation in this gene has been shown to result in polyhydramnios, megalencephaly, and symptomatic epilepsy (PMSE) syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their full-length nature is not known. [provided by RefSeq, Sep 2009].
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Ausgewählte STRADA Kategorien
STRADA Antikörper
High quality antibodies with extensive validation data.
STRADA Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene STRADA Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, IF, IHC (p), FACS
Validierungen
- (1)
- (5)
Kat. Nr.
ABIN1981302
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF, FACS
Validierungen
- (5)
Kat. Nr.
ABIN391217
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC (p), PLA
Validierungen
- (5)
Kat. Nr.
ABIN530101
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene STRADA Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1321741
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1321743
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN2131979
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren STRADA Produkten
: "GSK-3? controls autophagy by modulating LKB1-AMPK pathway in prostate cancer cells." in: The Prostate, (2015) (PubMed).: "Decreased SIRT1 expression and LKB1 phosphorylation occur with long-term high-fat diet feeding, in addition to AMPK phosphorylation impairment in the early phase." in: Obesity research & clinical practice, Vol. 4, Issue 3, pp. e163-246, (2013) (PubMed).
: "Humoral immunity to human breast cancer: antigen definition and quantitative analysis of mRNA expression." in: Cancer immunity, Vol. 1, pp. 4, (2003) (PubMed).
: "Activation of the tumour suppressor kinase LKB1 by the STE20-like pseudokinase STRAD." in: The EMBO journal, Vol. 22, Issue 12, pp. 3062-72, (2003) (PubMed).
Synonyme und alternative Namen zu STRADA
STE20-related kinase adaptor alpha (STRADA), ste20-related kinase adaptor alpha (strada), STE20-related kinase adaptor alpha (strada), STE20-related kinase adaptor alpha (Strada), 2610019A05Rik, 6030402H20Rik, AI480680, E130112C09Rik, fj99g05, lyk5, LYK5, Lyk5, NY-BR-96, PMSE, Stlk, STRAD, wu:fj99g05, zgc:56109Bezeichner auf Proteinebene für STRADA
- protein kinase LYK5
- STE20-related kinase adapter protein alpha
- STE20-related kinase adaptor alpha
- STE20-related kinase adapter protein alpha-like
- STE20-like pseudokinase
- STRAD alpha
- serologically defined breast cancer antigen NY-BR-96
- STE20-related adapter protein
Haben Sie etwas anderes gesucht?
- STRA8
- STRA6
- STRA13
- STR3
- STPG2
- STPG1
- STOX2
- STOX1
- Stonin 2
- STON1
- STOML2
- STOML1
- Stomatin (EPB72)-Like 3
- Stomatin
- STMN4
- STMN2
- STM
- STK40
- STK4
- STK39
- STRADB
- STRAP
- STRBP
- Streptavidin
- Streptococcal Pyrogenic Exotoxin A
- Streptococcal Pyrogenic Exotoxin B
- Streptococcus Agalactiae
- Streptococcus B
- Streptococcus Group A
- Streptococcus Group B
- Streptococcus Pneumoniae
- Streptokinase
- Streptokinase C
- Streptolysin O
- Streptomycin
- Striatin
- STRIP1
- STRIP2
- STRN3
- STRN4
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