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SUCNR1 Produkte

(Succinate Receptor 1 (SUCNR1))
This gene encodes a G-protein-coupled receptor for succinate, an intermediate molecule of the citric acid cycle. It is involved in the promotion of hematopoietic progenitor cell development, and it has a potential role in renovascular hypertension which has known correlations to renal failure, diabetes and atherosclerosis. [provided by RefSeq, Oct 2009].

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Ausgewählte SUCNR1 Kategorien

SUCNR1 Antikörper

High quality antibodies with extensive validation data.

SUCNR1 ELISA Kits

Reliable ELISA kits for a wide range of species.

SUCNR1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene SUCNR1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation ELISA, WB, IF, IHC
Validierungen
  • (4)
Kat. Nr. ABIN7170906
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation IHC, IHC (p)
Validierungen
  • (2)
Kat. Nr. ABIN1048897
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation ELISA, WB, IF, ICC
Validierungen
  • (2)
Kat. Nr. ABIN6265363
Menge 100 μL
Datenblatt Datenblatt

Empfohlene SUCNR1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method
Validierungen
Kat. Nr. ABIN1159995
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method
Validierungen
Kat. Nr. ABIN1159996
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method
Validierungen
Kat. Nr. ABIN1159997
Menge 96 tests
Datenblatt Datenblatt

Empfohlene SUCNR1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
Kat. Nr. ABIN1330532
Menge 2 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3106209
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3128076
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren SUCNR1 Produkten

Wu, Huang, Hsieh, Wang, Yen, Lee, Yeh, Peng, Kuo, Wen, Lin, Hsiao, Wu, Kung, Hsu, Kuo: "Cancer-Derived Succinate Promotes Macrophage Polarization and Cancer Metastasis via Succinate Receptor." in: Molecular cell, Vol. 77, Issue 2, pp. 213-227.e5, (2020) (PubMed).

Caielli, Veiga, Balasubramanian, Athale, Domic, Murat, Banchereau, Xu, Chandra, Chung, Walters, Baisch, Wright, Punaro, Nassi, Stewart, Fuller, Ucar, Ueno, Zhou, Banchereau, Pascual: "A CD4+ T cell population expanded in lupus blood provides B cell help through interleukin-10 and succinate." in: Nature medicine, Vol. 25, Issue 1, pp. 75-81, (2019) (PubMed).

Wang, Xu, Yuan, Xu, Zhang, Li, Wang, Yin, Zhang, Cai, Zhu, Xu, Liang, Schaul, Xie, Yue, Liao, Yu, Luo, Zhou, Yang, He, Du, Zhou, Deng, Wang, Gao, Zhu, Xi, Zhang, Shu, Jiang: "Succinate induces skeletal muscle fiber remodeling via SUNCR1 signaling." in: EMBO reports, Vol. 20, Issue 9, pp. e47892, (2019) (PubMed).

Nguyen, Park, Le, Park, Choi, Cho: "Metformin ameliorates activation of hepatic stellate cells and hepatic fibrosis by succinate and GPR91 inhibition." in: Biochemical and biophysical research communications, Vol. 495, Issue 4, pp. 2649-2656, (2018) (PubMed).

Peruzzotti-Jametti, Bernstock, Vicario, Costa, Kwok, Leonardi, Booty, Bicci, Balzarotti, Volpe, Mallucci, Manferrari, Donegà, Iraci, Braga, Hallenbeck, Murphy, Edenhofer, Frezza, Pluchino: "Macrophage-Derived Extracellular Succinate Licenses Neural Stem Cells to Suppress Chronic Neuroinflammation." in: Cell stem cell, Vol. 22, Issue 3, pp. 355-368.e13, (2018) (PubMed).

Mu, Zhao, Xu, Shi, Geng, Shen, Zhang, Pan, Yang, Hu, Lv, Wen, You: "Oncometabolite succinate promotes angiogenesis by upregulating VEGF expression through GPR91-mediated STAT3 and ERK activation." in: Oncotarget, Vol. 8, Issue 8, pp. 13174-13185, (2017) (PubMed).

Guo, Xie, Li, Yang, Yu, Zhang, Zhang, Saxena, Snyder, Wu, Li: "Succinate and its G-protein-coupled receptor stimulates osteoclastogenesis." in: Nature communications, Vol. 8, pp. 15621, (2017) (PubMed).

McCreath, Espada, Gálvez, Benito, de Molina, Sepúlveda, Cervera: "Targeted disruption of the SUCNR1 metabolic receptor leads to dichotomous effects on obesity." in: Diabetes, Vol. 64, Issue 4, pp. 1154-67, (2015) (PubMed).

Hu, Li, Du, Chen, Wang, Xiong, Wu: "The MAPK signaling pathway mediates the GPR91-dependent release of VEGF from RGC-5 cells." in: International journal of molecular medicine, Vol. 36, Issue 1, pp. 130-8, (2015) (PubMed).

Li, Hu, Du, Chen, Wang, Wu: "ERK1/2/COX-2/PGE2 signaling pathway mediates GPR91-dependent VEGF release in streptozotocin-induced diabetes." in: Molecular vision, Vol. 20, pp. 1109-21, (2014) (PubMed).

Synonyme und alternative Namen zu SUCNR1

succinate receptor 1 (SUCNR1), succinate receptor 1 (Sucnr1), GPR91, Gpr91

Bezeichner auf Proteinebene für SUCNR1

  • G protein-coupled receptor 91
  • G-protein coupled receptor 91
  • P2Y purinoceptor 1
  • succinate receptor 1
  • G-protein-coupled receptor 91
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