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SYN2 Produkte

(Synapsin II (SYN2))
This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family encodes a neuron-specific phosphoprotein that selectively binds to small synaptic vesicles in the presynaptic nerve terminal. The TIMP4 gene is located within an intron of this gene and is transcribed in the opposite direction. Mutations in this gene may be associated with abnormal presynaptic function and schizophrenia. Alternative splicing of this gene results in two transcripts. [provided by RefSeq, Jul 2008].

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Ausgewählte SYN2 Kategorien

SYN2 Antikörper

High quality antibodies with extensive validation data.

SYN2 ELISA Kits

Reliable ELISA kits for a wide range of species.

SYN2 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene SYN2 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, IHC, ELISA
Validierungen
  • (3)
Kat. Nr. ABIN7239083
Menge 200 μL
Datenblatt Datenblatt
Reaktivität Mouse
Applikation WB, IHC, ICC
Validierungen
  • (3)
Kat. Nr. ABIN5014371
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Pig, Rat
Applikation WB, IHC, IP, ICC
Validierungen
  • (2)
  • (2)
Kat. Nr. ABIN1742208
Menge 50 μg
Datenblatt Datenblatt

Empfohlene SYN2 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6959792
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6959793
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6209133
Menge 96 tests
Datenblatt Datenblatt

Empfohlene SYN2 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1321978
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7419376
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3073642
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren SYN2 Produkten

Raphael, Webb, Gomez-Rivera, Chase Huizar, Gupta, Arulanandam, Wang, Haskins, Forsthuber: "Serum Neuroinflammatory Disease-Induced Central Nervous System Proteins Predict Clinical Onset of Experimental Autoimmune Encephalomyelitis." in: Frontiers in immunology, Vol. 8, pp. 812, (2017) (PubMed).

Acuna, Liu, Südhof: "How to Make an Active Zone: Unexpected Universal Functional Redundancy between RIMs and RIM-BPs." in: Neuron, Vol. 91, Issue 4, pp. 792-807, (2016) (PubMed).

Jovasevic, Corcoran, Leaderbrand, Yamawaki, Guedea, Chen, Shepherd, Radulovic: "GABAergic mechanisms regulated by miR-33 encode state-dependent fear." in: Nature neuroscience, Vol. 18, Issue 9, pp. 1265-71, (2015) (PubMed).

Shulman, Stavsky, Fedorova, Mikulincer, Atias, Radinsky, Kahn, Slutsky, Gitler: "ATP binding to synaspsin IIa regulates usage and clustering of vesicles in terminals of hippocampal neurons." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 3, pp. 985-98, (2015) (PubMed).

Chen, Yu, Huang, Yu, Zhu, Lam, Lam, Zhou: "Prenatal transfer of polybrominated diphenyl ethers (PBDEs) results in developmental neurotoxicity in zebrafish larvae." in: Environmental science & technology, Vol. 46, Issue 17, pp. 9727-34, (2012) (PubMed).

Petersohn, Schoch, Brinkmann, Thiel: "The human synapsin II gene promoter. Possible role for the transcription factor zif268/egr-1, polyoma enhancer activator 3, and AP2." in: The Journal of biological chemistry, Vol. 270, Issue 41, pp. 24361-9, (1995) (PubMed).

Ferreira, Kosik, Greengard, Han: "Aberrant neurites and synaptic vesicle protein deficiency in synapsin II-depleted neurons." in: Science (New York, N.Y.), Vol. 264, Issue 5161, pp. 977-9, (1994) (PubMed).

Thiel, Südhof, Greengard: "Synapsin II. Mapping of a domain in the NH2-terminal region which binds to small synaptic vesicles." in: The Journal of biological chemistry, Vol. 265, Issue 27, pp. 16527-33, (1990) (PubMed).

Südhof, Czernik, Kao, Takei, Johnston, Horiuchi, Kanazir, Wagner, Perin, De Camilli: "Synapsins: mosaics of shared and individual domains in a family of synaptic vesicle phosphoproteins." in: Science (New York, N.Y.), Vol. 245, Issue 4925, pp. 1474-80, (1989) (PubMed).

Synonyme und alternative Namen zu SYN2

synapsin II L homeolog (syn2.L), synapsin II (SYN2), synapsin IIa (syn2a), synapsin II S homeolog (syn2.S), synapsin-2 (EDI_190690), synapsin II (Syn2), 2900074L19Rik, AI836018, AI841723, MGC115109, syn1, syn2, SYN2, synII, SYNII, synIIa, SYNIIa, synIIb, SYNIIb, zgc:92311

Bezeichner auf Proteinebene für SYN2

  • synapsin II
  • synapsin IIa
  • synapsin-2
  • synapsin2
  • synapsin-2-like
  • synapsin 2
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