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TAP2 Produkte

(Transporter 2, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP2))
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene is located 7 kb telomeric to gene family member ABCB2. The protein encoded by this gene is involved in antigen presentation. This protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Alternative splicing of this gene produces two products which differ in peptide selectivity and level of restoration of surface expression of MHC class I molecules. [provided by RefSeq, Jul 2008].

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Ausgewählte TAP2 Kategorien

TAP2 Antikörper

High quality antibodies with extensive validation data.

TAP2 ELISA Kits

Reliable ELISA kits for a wide range of species.

TAP2 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene TAP2 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IF
Validierungen
  • (7)
Kat. Nr. ABIN3022237
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, ELISA, IF (p), IF (cc), FACS, IHC (fro), IHC (p)
Validierungen
  • (3)
Kat. Nr. ABIN680123
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, FACS
Validierungen
  • (2)
Kat. Nr. ABIN6243497
Menge 200 μL
Datenblatt Datenblatt

Empfohlene TAP2 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method
Validierungen
Kat. Nr. ABIN1122075
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method
Validierungen
Kat. Nr. ABIN1122077
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method
Validierungen
Kat. Nr. ABIN1122076
Menge 96 tests
Datenblatt Datenblatt

Empfohlene TAP2 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1322144
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7419364
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Rat
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7419367
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren TAP2 Produkten

Feigenberg, Clarke, Virtanen, Plotkin, Letarte, Rosen, Bernardini, Kollara, Brown, Murphy: "Molecular profiling and clinical outcome of high-grade serous ovarian cancer presenting with low- versus high-volume ascites." in: BioMed research international, Vol. 2014, pp. 367103, (2014) (PubMed).

Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).

Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, (2002) (PubMed).

Tang, Freedman, Allen, Karita, Musonda, Braga, Jamieson, Louie, Kaslow: "Genotyping TAP2 variants in North American Caucasians, Brazilians, and Africans." in: Genes and immunity, Vol. 2, Issue 1, pp. 32-40, (2001) (PubMed).

Synonyme und alternative Namen zu TAP2

transporter 2, ATP binding cassette subfamily B member (TAP2), transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) (Tap2), transporter 2, ATP binding cassette subfamily B member (Tap2), ABC18, ABCB3, Abcb3, AI462429, APT2, Cim, D6S217E, Ham-2, Ham2, jas, MTP2, PSF-2, PSF2, RING11, Tap-2, Y1

Bezeichner auf Proteinebene für TAP2

  • ABC transporter, MHC 2
  • ATP-binding cassette, sub-family B (MDR/TAP), member 3
  • antigen peptide transporter 2
  • peptide supply factor 2
  • peptide transporter PSF2
  • peptide transporter involved in antigen processing 2
  • really interesting new gene 11 protein
  • transporter 2, ABC (ATP binding cassette)
  • ATP dependent transport protein family member
  • ATP-binding cassette sub-family B member 3
  • histocompatibility antigen modifier 2
  • APT2
  • Transporter 2 ABC (ATP binding cassette)
  • ABC-transporter
  • transporter 2, ABC(ATP binding cassette)
  • transporter 2, ATP-binding cassette, sub-family B
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