T-Box 5 Produkte
(T-Box 5 (TBX5))
Kategorien
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The encoded protein may play a role in heart development and specification of limb identity. Mutations in this gene have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs. Several transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].
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Ausgewählte T-Box 5 Kategorien
T-Box 5 Antikörper
High quality antibodies with extensive validation data.
T-Box 5 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene T-Box 5 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, RNAi
Validierungen
- (3)
- (3)
Kat. Nr.
ABIN563098
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC
Validierungen
- (3)
Kat. Nr.
ABIN7239203
Menge
200 μL
Datenblatt
Datenblatt
Reaktivität
Bat, Chicken, Cow, Dog, Goat, Guinea Pig, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat, Sheep, Xenopus laevis, Zebrafish (Danio rerio)
Applikation
WB, IHC, IHC (p)
Validierungen
- (3)
Kat. Nr.
ABIN6741551
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene T-Box 5 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6221767
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene T-Box 5 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1322304
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1322302
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7423756
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren T-Box 5 Produkten
: "A Comprehensive TALEN-Based Knockout Library for Generating Human-Induced Pluripotent Stem Cell-Based Models for Cardiovascular Diseases." in: Circulation research, Vol. 120, Issue 10, pp. 1561-1571, (2017) (PubMed).: "TBX5 mutations contribute to early-onset atrial fibrillation in Chinese and Caucasians." in: Cardiovascular research, Vol. 109, Issue 3, pp. 442-50, (2016) (PubMed).
: "Single-Cell Expression Profiling Reveals a Dynamic State of Cardiac Precursor Cells in the Early Mouse Embryo." in: PLoS ONE, Vol. 10, Issue 10, pp. e0140831, (2015) (PubMed).
: "Kctd10 regulates heart morphogenesis by repressing the transcriptional activity of Tbx5a in zebrafish." in: Nature communications, Vol. 5, pp. 3153, (2014) (PubMed).
: "Holt-Oram syndrome with intermediate atrioventricular canal defect, and aortic coarctation: functional characterization of a de novo TBX5 mutation." in: American journal of medical genetics. Part A, Vol. 164A, Issue 6, pp. 1419-24, (2014) (PubMed).
: "Directing cardiomyogenic differentiation of human pluripotent stem cells by plasmid-based transient overexpression of cardiac transcription factors." in: Stem cells and development, Vol. 22, Issue 7, pp. 1112-25, (2013) (PubMed).
: "Phenanthrene exposure causes cardiac arrhythmia in embryonic zebrafish via perturbing calcium handling." in: Aquatic toxicology (Amsterdam, Netherlands), Vol. 142-143, pp. 26-32, (2013) (PubMed).
: "Directed cardiomyocyte differentiation from human pluripotent stem cells by modulating Wnt/β-catenin signaling under fully defined conditions." in: Nature protocols, Vol. 8, Issue 1, pp. 162-75, (2012) (PubMed).
: "Induction of apoptosis and inhibition of cell growth by tbx5 knockdown contribute to dysmorphogenesis in Zebrafish embryos." in: Journal of biomedical science, Vol. 18, pp. 73, (2011) (PubMed).
: "Physical interaction between TBX5 and MEF2C is required for early heart development." in: Molecular and cellular biology, Vol. 29, Issue 8, pp. 2205-18, (2009) (PubMed).
Synonyme und alternative Namen zu T-Box 5
T-box 5 (TBX5), T-box 5 (tbx5), T-box 5 L homeolog (tbx5.L), T-box 5 (Tbx5), T-box 5a (tbx5a), HOS, tbx-5, TBX5, tbx5, tbx5.1, xtbx-5, xtbx5, zf-tbx5, zTbx5Bezeichner auf Proteinebene für T-Box 5
- T-box 5
- T-box protein 5
- T-box transcription factor 5
- T-box transcription factor TBX5
- T-box transcription factor TBX5-like
- t-box transcription factor TBX5-like
- T-box gene 5
- T-box gene 5.1
- T-box transcription factor TBX5-A
- etID310031.5
- heartstrings
- hst
- zftbx5a
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