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TBK1 Produkte

(TANK-Binding Kinase 1 (TBK1))

Kategorien

The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. [provided by RefSeq, Oct 2010].

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Ausgewählte TBK1 Kategorien

TBK1 Antikörper

High quality antibodies with extensive validation data.

TBK1 ELISA Kits

Reliable ELISA kits for a wide range of species.

TBK1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene TBK1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse
Applikation WB, IHC (p)
Validierungen
  • (1)
  • (5)
Kat. Nr. ABIN392371
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC
Validierungen
  • (6)
Kat. Nr. ABIN3016268
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IP, IF
Validierungen
  • (6)
Kat. Nr. ABIN7270723
Menge 100 μL
Datenblatt Datenblatt

Empfohlene TBK1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Analytical Method Semi-Quantitative Sandwich ELISA
Validierungen
  • (3)
Kat. Nr. ABIN4889796
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6970559
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6959861
Menge 96 tests
Datenblatt Datenblatt

Empfohlene TBK1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1322250
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1322248
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
Kat. Nr. ABIN5509171
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren TBK1 Produkten

Hu, Pan, Cheng, Zhang, Wang, Chen, Zhu, Liu, Yang, Wu, Zhao, Huang, Zhang, Mao, Ou, Yu, Zhang, Liu, Tian, Pan, Rehman, Yin, Jia: "Autophagy Promotes Duck Tembusu Virus Replication by Suppressing p62/SQSTM1-Mediated Innate Immune Responses In Vitro." in: Vaccines, Vol. 8, Issue 1, (2020) (PubMed).

Wan, Chen, Li, Pang, Chen, Nie, Pan, Qiao, Bao: "Porcine FcγRIIb mediated PRRSV ADE infection through inhibiting IFN-β by cytoplasmic inhibitory signal transduction." in: International journal of biological macromolecules, Vol. 138, pp. 198-206, (2020) (PubMed).

Gulen, Koch, Haag, Schuler, Apetoh, Villunger, Radtke, Ablasser: "Signalling strength determines proapoptotic functions of STING." in: Nature communications, Vol. 8, Issue 1, pp. 427, (2018) (PubMed).

Jiang, Song, Li, Xue, Deng, Li, Liu, Wang: "Capsular Polysaccharide is a Main Component of Mycoplasma ovipneumoniae in the Pathogen-Induced Toll-Like Receptor-Mediated Inflammatory Responses in Sheep Airway Epithelial Cells." in: Mediators of inflammation, Vol. 2017, pp. 9891673, (2018) (PubMed).

Wuerth, Habjan, Wulle, Superti-Furga, Pichlmair, Weber: "NSs Protein of Sandfly Fever Sicilian Phlebovirus Counteracts Interferon (IFN) Induction by Masking the DNA-Binding Domain of IFN Regulatory Factor 3." in: Journal of virology, Vol. 92, Issue 23, (2018) (PubMed).

Takahashi, Loo, Okada, Kamachi, Watanabe, Wakita, Watanabe, Kawamoto, Miyata, Barber, Ohtani, Hara: "Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells." in: Nature communications, Vol. 9, Issue 1, pp. 1249, (2018) (PubMed).

Kwon, Park, Sesaki, Kang: "Carbonyl cyanide 3-chlorophenylhydrazone (CCCP) suppresses STING-mediated DNA sensing pathway through inducing mitochondrial fission." in: Biochemical and biophysical research communications, Vol. 493, Issue 1, pp. 737-743, (2017) (PubMed).

Slowicka, Vereecke, Mc Guire, Sze, Maelfait, Kolpe, Saelens, Beyaert, van Loo: "Optineurin deficiency in mice is associated with increased sensitivity to Salmonella but does not affect proinflammatory NF-κB signaling." in: European journal of immunology, Vol. 46, Issue 4, pp. 971-80, (2016) (PubMed).

Mukawera, Chartier, Williams, Pagano, Lapointe, Grandvaux: "Redox-modulating agents target NOX2-dependent IKKε oncogenic kinase expression and proliferation in human breast cancer cell lines." in: Redox biology, Vol. 6, pp. 9-18, (2015) (PubMed).

Yu, Croxen, Marchiando, Ferreira, Cadwell, Foster, Finlay: "Autophagy facilitates Salmonella replication in HeLa cells." in: mBio, Vol. 5, Issue 2, pp. e00865-14, (2014) (PubMed).

Synonyme und alternative Namen zu TBK1

TANK binding kinase 1 L homeolog (tbk1.L), TANK binding kinase 1 (TBK1), TANK-binding kinase 1 (tbk1), TANK binding kinase 1 (tbk1), TANK-binding kinase 1 (Tbk1), 1200008B05Rik, AI462036, AW048562, nak, NAK, t2k, T2K, TBK1, wu:fk70c05, zgc:136548

Bezeichner auf Proteinebene für TBK1

  • serine/threonine-protein kinase TBK1
  • TANK-binding kinase 1
  • NF-kappa-B-activating kinase
  • TANK binding kinase 1
  • serine/threonine protein kinase TBK1
  • serine/threonine-protein kinase TBK1-like
  • NF-kB-activating kinase
  • T2K
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