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TCL1A Produkte

(T-Cell Leukemia/lymphoma 1A (TCL1A))

Kategorien

Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha (MIM 186880) or TCR-beta (MIM 186930) regulatory elements (summarized by Virgilio et al., 1998 [PubMed 9520462]). In normal T cells TCL1 is expressed in CD4-/CD8- cells, but not in cells at later stages of differentiation. TCL1 functions as a coactivator of the cell survival kinase AKT (MIM 164730) (Laine et al., 2000 [PubMed 10983986]).[supplied by OMIM, Jul 2010].

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Ausgewählte TCL1A Kategorien

TCL1A Antikörper

High quality antibodies with extensive validation data.

TCL1A ELISA Kits

Reliable ELISA kits for a wide range of species.

TCL1A Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene TCL1A Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, StM
Validierungen
  • (5)
Kat. Nr. ABIN6940949
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, FACS
Validierungen
  • (4)
Kat. Nr. ABIN5542543
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation IHC, StM
Validierungen
  • (4)
Kat. Nr. ABIN6940948
Menge 100 μg
Datenblatt Datenblatt

Empfohlene TCL1A ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method
Validierungen
Kat. Nr. ABIN456531
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method
Validierungen
Kat. Nr. ABIN1160655
Menge 96 tests
Datenblatt Datenblatt

Empfohlene TCL1A Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN935060
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1322390
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1322394
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren TCL1A Produkten

Ho, Bongartz, Liu, Kalari, Goss, Shepherd, Goetz, Kubo, Ingle, Wang, Weinshilboum: "Estrogen, SNP-Dependent Chemokine Expression and Selective Estrogen Receptor Modulator Regulation." in: Molecular endocrinology (Baltimore, Md.), Vol. 30, Issue 3, pp. 382-98, (2016) (PubMed).

Harbuzariu, Kim, Meyer, Donnenberg, Tillman: "CD34 affinity pheresis attenuates a surge among circulating progenitor cells following vascular injury." in: Journal of vascular surgery, Vol. 59, Issue 6, pp. 1686-94, (2014) (PubMed).

Gahagan, Scrymgeour, Casson, Gopalan, Robinson: "Integrated high-power electro-optic lens and large-angle deflector." in: Applied optics, Vol. 40, Issue 31, pp. 5638-42, (2008) (PubMed).

Rodig, Vergilio, Shahsafaei, Dorfman: "Characteristic expression patterns of TCL1, CD38, and CD44 identify aggressive lymphomas harboring a MYC translocation." in: The American journal of surgical pathology, Vol. 32, Issue 1, pp. 113-22, (2007) (PubMed).

Pescarmona, Remotti, Perez, Monaco, Pacchiarotti, Faraggiana, Russo, Baroni: "Expression of TCL1 and CD27 in primary cutaneous B-cell lymphomas." in: Histopathology, Vol. 49, Issue 4, pp. 343-8, (2006) (PubMed).

Shen, Ferguson, Renard, Hoyer, Kim, Hao, Alt, Roeder, Morse, Teitell: "Dysregulated TCL1 requires the germinal center and genome instability for mature B-cell transformation." in: Blood, Vol. 108, Issue 6, pp. 1991-8, (2006) (PubMed).

Roos, Hennig, Schwaller, Zbären, Dummer, Burg, Tobler, Virgilio, Croce, Fey, Borisch: "Expression of TCL1 in hematologic disorders." in: Pathobiology : journal of immunopathology, molecular and cellular biology, Vol. 69, Issue 2, pp. 59-66, (2001) (PubMed).

Pekarsky, Hallas, Croce: "The role of TCL1 in human T-cell leukemia." in: Oncogene, Vol. 20, Issue 40, pp. 5638-43, (2001) (PubMed).

Nakayama, Murao, Kitazawa, Azumi, Yamamoto, Maeda: "Activation of the TCL1 protein in B cell lymphomas." in: Pathology international, Vol. 50, Issue 3, pp. 191-9, (2000) (PubMed).

Narducci, Pescarmona, Lazzeri, Signoretti, Lavinia, Remotti, Scala, Baroni, Stoppacciaro, Croce, Russo: "Regulation of TCL1 expression in B- and T-cell lymphomas and reactive lymphoid tissues." in: Cancer research, Vol. 60, Issue 8, pp. 2095-100, (2000) (PubMed).

Synonyme und alternative Namen zu TCL1A

T-cell leukemia/lymphoma 1A (TCL1A), T cell lymphoma breakpoint 1 (Tcl1), T-cell leukemia/lymphoma 1A (Tcl1a), TCL1, Tcl1, TCL1A, Tcl1a

Bezeichner auf Proteinebene für TCL1A

  • T-cell leukemia/lymphoma 1A
  • T-cell lymphoma-1
  • T-cell leukemia/lymphoma protein 1A
  • T-cell lymphoma breakpoint 1
  • TCL-1
  • oncogene TCL-1
  • oncogene TCL1
  • protein p14 TCL1
  • T-cell leukemia/lymphoma protein 1A (P14 TCL1 protein) (TCL1 oncogene) (TCL-1 protein)
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