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TDO2 Produkte

(Tryptophan 2,3-Dioxygenase (TDO2))

Kategorien

This gene encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein and subsequent kynurenine production may also play a role in cancer through the suppression of antitumor immune responses, and single nucleotide polymorphisms in this gene may be associated with autism. [provided by RefSeq, Feb 2012].

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Ausgewählte TDO2 Kategorien

TDO2 Antikörper

High quality antibodies with extensive validation data.

TDO2 ELISA Kits

Reliable ELISA kits for a wide range of species.

TDO2 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene TDO2 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IHC (p)
Validierungen
  • (10)
Kat. Nr. ABIN1501352
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Dog, Human, Pig
Applikation WB, IHC
Validierungen
  • (7)
Kat. Nr. ABIN2782334
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB
Validierungen
  • (1)
  • (3)
Kat. Nr. ABIN520811
Menge 50 μg
Datenblatt Datenblatt

Empfohlene TDO2 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6970915
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6960224
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Competition ELISA
Validierungen
Kat. Nr. ABIN511131
Menge 96 tests
Datenblatt Datenblatt

Empfohlene TDO2 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1322430
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1322432
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (2)
Kat. Nr. ABIN2733390
Menge 20 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren TDO2 Produkten

Hao, Huang, Feng, Li, Wang, Wang, Wu, Wan, Zhang, Zhang: "Non-NF2 mutations have a key effect on inhibitory immune checkpoints and tumor pathogenesis in skull base meningiomas." in: Journal of neuro-oncology, Vol. 144, Issue 1, pp. 11-20, (2019) (PubMed).

Wang, Do, Liu, Wang, Qu, Ke, Luo, Tang, Tang, Hu, Anderson, Liu, Gao: "Functional role of kynurenine and aryl hydrocarbon receptor axis in chronic rhinosinusitis with nasal polyps." in: The Journal of allergy and clinical immunology, Vol. 141, Issue 2, pp. 586-600.e6, (2018) (PubMed).

Woodling, Colas, Wang, Minhas, Panchal, Liang, Mhatre, Brown, Ko, Zagol-Ikapitte, van der Hart, Khroyan, Chuluun, Priyam, Milne, Rassoulpour, Boutaud, Manning-Boğ, Heller, Andreasson: "Cyclooxygenase inhibition targets neurons to prevent early behavioural decline in Alzheimer's disease model mice." in: Brain : a journal of neurology, Vol. 139, Issue Pt 7, pp. 2063-81, (2016) (PubMed).

Guastella, Michelhaugh, Klinger, Kupsky, Polin, Muzik, Juhász, Mittal: "Tryptophan PET Imaging of the Kynurenine Pathway in Patient-Derived Xenograft Models of Glioblastoma." in: Molecular imaging, Vol. 15, (2016) (PubMed).

Novikov, Wang, Stanford, Parks, Ramirez-Cardenas, Landesman, Laklouk, Sarita-Reyes, Gusenleitner, Li, Monti, Manteiga, Lee, Sherr: "An Aryl Hydrocarbon Receptor-Mediated Amplification Loop That Enforces Cell Migration in ER-/PR-/Her2- Human Breast Cancer Cells." in: Molecular pharmacology, Vol. 90, Issue 5, pp. 674-688, (2016) (PubMed).

Bosnyák, Kamson, Guastella, Varadarajan, Robinette, Kupsky, Muzik, Michelhaugh, Mittal, Juhász: "Molecular imaging correlates of tryptophan metabolism via the kynurenine pathway in human meningiomas." in: Neuro-oncology, Vol. 17, Issue 9, pp. 1284-92, (2015) (PubMed).

Xiao, Li, Jones-Brando, Yolken: "Abnormalities of neurotransmitter and neuropeptide systems in human neuroepithelioma cells infected by three Toxoplasma strains." in: Journal of neural transmission (Vienna, Austria : 1996), Vol. 120, Issue 12, pp. 1631-9, (2013) (PubMed).

Ohira, Hagihara, Toyama, Takao, Kanai, Funakoshi, Nakamura, Miyakawa: "Expression of tryptophan 2,3-dioxygenase in mature granule cells of the adult mouse dentate gyrus." in: Molecular brain, Vol. 3, Issue 1, pp. 26, (2010) (PubMed).

Synonyme und alternative Namen zu TDO2

tryptophan 2,3-dioxygenase b (tdo2b), tryptophan 2,3-dioxygenase (tdo2), tryptophan 2,3-dioxygenase (TDO2), tryptophan 2,3-dioxygenase (MADE_02822), tryptophan 2,3-dioxygenase (CtCNB1_3657), tryptophan 2,3-dioxygenase a (tdo2a), tryptophan 2,3-dioxygenase (CNC04830), tryptophan 2,3-dioxygenase (tdo), tryptophan 2,3-dioxygenase (Mrub_2119), tryptophan 2,3-dioxygenase (Deipr_2235), tryptophan 2,3-dioxygenase (Acav_1166), tryptophan 2,3-dioxygenase (Mesop_4278), tryptophan 2,3-dioxygenase (Tdo2), tryptophan 2,3-dioxygenase L homeolog (tdo2.L), AA407491, chky, DDBDRAFT_0190495, DDBDRAFT_0231363, DDB_0190495, DDB_0231363, fb62b10, fi30d08, TDO, Tdo, Tdo2, TDO2, tdo2, tdo2l, TO, TPH2, TRPO, wu:fb62b10, wu:fi30d08, zgc:63488, zgc:103693

Bezeichner auf Proteinebene für TDO2

  • TDO-B
  • TO-B
  • TRPO-B
  • tryptamin 2,3-dioxygenase B
  • tryptophan 2,3-dioxygenase B
  • tryptophan 2,3-dioxygenase, like
  • tryptophan oxygenase B
  • tryptophan pyrrolase B
  • tryptophanase B
  • TDO
  • TO
  • TRPO
  • tryptamin 2,3-dioxygenase
  • tryptophan oxygenase
  • tryptophan pyrrolase
  • tryptophanase
  • tryptophan 2,3-dioxygenase
  • TDO-A
  • TO-A
  • TRPO-A
  • tryptamin 2,3-dioxygenase A
  • tryptophan 2,3-dioxygenase A
  • tryptophan oxygenase A
  • tryptophan pyrrolase A
  • tryptophanase A
  • tdo variant1
  • tdo variant2
  • tryptophan-2,3-dioxygenase
  • tryptophan-23-dioxygenase
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